I am a mother of a transgender daughter who is 15 and started blockers and estradiol therapy when she was 14. Unfortunately she went through puberty quite young at about 10 leaving her with irreversible masculine changes like her voice and her skeleton she cannot accept and dragged her into her spiral of depression, anxiety and suicidal thoughts and we tried anything to help and it doesn’t work. I would like to start a petition  to see they could start a research into reversing the effects of puberty (testosterone/estrogen) she mentioned to me that she thought if they took the testosterone hormone and genetically modified the hormones to do the opposite. For example testosterone triggers the cartilage cells to grow in order to make the voice deeper if you can create a synthetic hormone that does the opposite we can stimulate the cartilage cells to deconstruct therefore reverse the effects. It is quite simple really just there is not much effort put into for research for trans people. I feel like this could really help the trans community in the future, if this is done and can relieve a ton of dysphoria that is experienced.
kind regards Valentina Koppa