Petition for the immediate withdrawal of Simparica (flea & tick treatment) from the market

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Controversial tick and flea "remedies" Nexgard and Bravecto were both approved and released in late 2013 and early 2014 respectively. Ever since, the controversy around these products has been increasing on a continuous basis. Both of these drugs already have quite an impressive legacy of suspicion of causing extremely serious adverse reactions, including the death of several hundred of innocent Canine victims.

March 2016 saw the addition of Simparica, yet another so-called Isoxazoline flea and tick “remedy”… and already several dogs have been adversely affected by this new drug.

It is yet too soon to state an accurate number of dogs that have been affected, but for such a young drug, the growing total of already reported adverse reactions is concerning. The 26 reported cases stated have occurred between the release date March 2016 and Jul 2016. Considering the fact that the drug had by Jul 2016 only been on the market for 4 months, this is very good reason to doubt the safety of this drug. In view of what had already been reported for its two sister drugs, it would be fair to assume that Simparica is going the same way.

These drugs are supposed to protect our pets by killing the pests that invade the lives of animals. At least that part of the promise holds true: they are deadly to ticks and fleas...

If it ended there, and the quality of our pets' lives were improved by these so-called “remedies”, they would have been welcomed with  open arms... but it doesn't end with killing the pests; numerous side effects have been experienced by many beloved pets and reported by their owners, including severe gastritis, vomiting, bloody diarrhea, seizures and even several deaths. Many dogs died after having ingested an Isoxazoline drug.

In spite of numerous calls to Merial, Merck and the FDA and lately also to Zoetis, the manufacturer of Simarica, our problem seems to be ignored. And now, after the sad passing of Cuddles, the very dear and beloved Canine friend of Susan Rae, following a dose of Simparica, I feel that it is time to take action. Please read the posts on this public Facebook group:

and this one:

and this one:

The story of Cuddles by Susan Rae:

While she was still alive, after the drug was administered:

“I spent the entire day at the Emergency Veterinary Clinic. My Baby has liver disease and acute pancreatitis. Cuddles is with me 24/7 since I am currently homebound. I really miss having her with me. She has to stay in the hospital for a few days and can come home if things go ok. I am so sad and depressed. I have been crying all day. I love that little dog”

After the sad event of her passing:

“I want to thank you for adding me to your group. I just wish I would have known about this a couple weeks ago. Through research I have found that Simparica, Bravecto, and Nexguard all have one thing in common, they kill dogs! We had to put our sweet, sweet Cuddles to sleep a week ago. She was a little, precious toy poodle. Our Vet called Cuddles a miracle dog. She was 15 1/2 and probably would have lived a few more years if I had not given her Simparica. Throughout her life Cuddles had liver disease, Cushing disease, pancreatitis, and the last few years, some kidney problems. Although she was not in kidney failure. She was on medication for all of these diseases and I gave her the best medical care possibly. The is why she lived so long. Cuddles had NEVER had fleas in her life. She was licking so I took her to the vets. Her bowels and blood test came out fine. Her kidneys and liver had even improved, but she did have fleas. He gave me a free sample of Simparica and told me to give her one that afternoon. I gave it to her at 4 and by 6 she had diarrhea. Later that evening she had pure blood coming out of her with dry heaves. Then the tremors started. I had to take her to the emergency clinic. Total waste of time. My vets the next day. He didn't think it was from the pill. She got worse and we were up with her all night. She was bleeding to death internally, vomiting, tremors, unsteady, would fall when she would try to walk, salivating. Would lean against the wall and hang her head down. It broke my heart to see the pain I put her through by giving her Simparica. We put her to sleep early that morning. I am having a very hard time forgiving myself and don't know if I ever will. Please do not give your dog any of these pills. Cuddles was fine and tests were great that morning. Thank you for letting me share this awful time in my life. I hope it will help save another dog's life.”

Here is a link to the combined ADE report for Bravecto, Nexgard and Simparica:

Here are links to articles by two well-known holistic veterinarians on these three drugs:

After reading the story of Cuddles as posted directly from Susan Rae's Facebook profile, as well as the attached ADE report and the two articles on the safety of the Isoxazoline drugs, please decide for yourself. Is a third Isoxazoline drug really necessary while the two older ones have not even been proven beyond doubt to be safe for our furkids?

And then please do the right thing by signing this petition. We need this drug, and the other two, to be withdrawn from the veterinary scene with immediate effect. And we need them to stay off the market. Our dogs do not need these drugs, as there are other much safer methods to combat the problems that these drugs are supposed to combat but are in fact aggravating because of the horrible side effects.

Think about it:

Your dog can still contract a tick borne disease because the drugs don’t even repel the parasites. They have to bite and attach to the dog and take a toxic blood meal off the victim in order to die…

Thank you

Antoinette LeRoux