Disney Amphibia creator Matt Braly said that he'd love to make a full disc release for his series, with commentary tracks and extra content and whatnot. 

The demand for physical media is at an all time low in this age of streaming, but if the internet makes enough noise while shaking wads of money in the air, the Shout! Factory company (already publishers of the Gravity Falls Complete Series) might be interested into the possibility of making it a reality.

Artwork by Matt Braly