This update is a continuation of a series regarding the controversial publication offered through CABI’s Digital Library: (Promoted worldwide)

Lyme Disease An Evidence-based Approach 3rd Edition -John Halperin
https://www.cabidigitallibrary.org/doi/book/10.1079/9781800626225.0000

The chapter; “Lyme Disease in Children” by Eugene D. Shapiro is a continuation of the decades long disinformation surrounding Lyme disease. Based on his quotes archived on the site below, one might get the impression that this individual is a fool with a medical degree. 

Previous updates in this CABI Digital Library series: Part 1, 2, 3, 4, 5

Picture of Shapiro was found here on the Yale School of Medicine Website.

Ongoing communication with CABI’s Managing Director of Publishing, Andy Robinson and Damian Bird, Publishing & Operations Director:

---------- Original Message ----------
From: CARL TUTTLE <runagain@comcast.net>
To: Andy Robinson <A.Robinson@cabi.org>
Cc: Damian Bird <D.Bird@cabi.org>
Date: 09/18/2025 8:51 AM EDT
Subject: CABI Digital Library: “There is no evidence that congenital Lyme disease is a significant problem.” -Eugene D. Shapiro
 
 
CABI Digital Library
 
Lyme Disease in Children
https://www.cabidigitallibrary.org/doi/abs/10.1079/9781800626225.0009
 
Author: Eugene D. Shapiro
 
“There is no evidence that congenital Lyme disease is a significant problem.”
 
 
Drs. Robinson and Bird,
 
Eugene D. Shapiro, MD is often heard spreading disinformation as an archived list of his quotes with inaccuracies can be found here: “Memorable and Not So Memorable Quotes by Lyme Disease Denialists” In the New England Journal of Medicine article, “Lyme Disease” Shapiro is quoted, “no documented cases of congenital Lyme”
 
 
Though scientists have known Lyme is congenital since 1985, it took the CDC until 2020 to finally acknowledge this fact. CDC Fact Sheet: Pregnancy and Lyme Disease (See attachment of 28 studies reporting congenital Lyme)
 
 
In 2022 the advocacy group Mothers Against Lyme co-sponsored by Project Lyme demanded more research:
 
 
Congress Commends NIH Collaboration with Advocacy Groups to Advance Research on Maternal-Fetal Transmission of Lyme Disease
https://www.webwire.com/ViewPressRel.asp?aId=284113
 
Appropriations directives encourage NIH to intensify research on links between Lyme disease during pregnancy and adverse birth outcomes.
 
 
Shapiro Quotes: 
  
"Lyme disease prevention requires only minimal precautions; even for people living in areas with the highest  concentration of positively identified cases": 

-Eugene D. Shapiro, MD, Yale Children's Health Letter, April 1995  

  
"Over time, the [Lyme] disease tends to burn itself out, even without treatment, in many people":  

-Eugene Shapiro, MD, quoted by Karen Freeman in The New York Times, October 24, 1996  

  
"Children with only non-specific symptoms, such as headache, fatigue, or arthralgia, are very unlikely to have Lyme disease. Serologic tests for Lyme disease should not be ordered for such patients because a positive test result is very likely to be a false-positive": 

-Eugene D. Shapiro, MD, in ACP's Lyme Disease, page 131  

"Nearly 90% of children who develop Lyme disease have either single or multiple sites of erythema migrans": 

-Eugene D. Shapiro, MD, ibid., page 132  

  
"As many as 40% of the patients with well-documented late stage Lyme disease will not have had a preceding lesion of erythema migrans . . . as the only clinical manifestation of early Lyme disease. . . . The existence of a flu-like illness without erythema migrans of early Lyme disease has been clearly established":  

-Eugene D. Shapiro, MD, et al., "Early Lyme Disease: A Flu- like Illness Without Erythema Migrans," Pediatrics 91,  
(1993): 456-59  

  
"There is no evidence that congenital Lyme disease is a problem":  

-Eugene D. Shapiro, MD, in ACP's Lyme Disease, page 132  

  
"The prognosis of children with Lyme disease, both early and late, is excellent, with no evidence of chronic symptoms or long- term sequelae": 

-Eugene D. Shapiro, MD, ibid., page 132  

  
"Because of the low risk of Lyme disease and the excellent prognosis of children who do develop Lyme disease,  prophylactic antimicrobial treatment is not recommended for children who are bitten by a deer tick": 

-Eugene D.Shapiro, MD, ibid., page  

  
"In patients presenting with nonspecific symptoms, the positive predictive value of serologic testing for Lyme disease is low": 

-Eugene D. Shapiro, MD, ACP's Lyme Disease, page 224  

  
"There are a ton of people with non-specific symptoms and most of their positives are false positives [for the ELISA and Western Blot], so they think they have this diagnosis of Lyme":  

-Eugene Shapiro, MD, quoted by Stefanie Ramp in the Fairfield County Weekly, May 20, 1999  

  
"If all you know is that you found a deer tick on your child, the risk is 1 to 2 percent at most of having Lyme disease.  And then greater than 90 percent of those will show a rash at the site of the bite.": 

-Eugene Shapiro, MD, in the April 1995 issue of Yale Children's Health Letter  

  
"Most ticks are not infected and even if a child has been bitten by an infected tick, 36 to 48 hours are needed before transmission of the bacteria takes place.": 

-Eugene Shapiro, MD, ibid.  

  
"There are probably better ways to spend health-care dollars" than on a vaccine for Lyme disease: 

-Eugene Shapiro, MD in the April 1995 issue of Yale Children's Health Letter  

  
"It [LYMErix vaccine] is fairly expensive, and I think that the biggest problem is not Lyme disease but anxiety about Lyme disease, and I'm not sure how effective the vaccine is against anxiety about Lyme disease....I don't think most people are at really high risk for Lyme disease, so the benefits don't necessarily qualify the costs.": 

-Eugene Shapiro, MD, a professor of pediatrics at Yale, quoted by Stefanie Ramp in the Fairfield Co. Weekly on  
May 20, 1999  
  
"It's usually not Lyme disease unless it looks, smells, and tastes like Lyme disease":  

-Eugene Shapiro, MD, in the April 1995 issue of Yale Children's Health Letter  

If you only go to a Lyme literate doctor, you are likely to be diagnosed with Lyme disease, because that's what they do. If you go to Midas, you're going to get a muffler. (Chronic Lyme sufferers believe that the medical world would benefit immensely from Shapiro having a Midas muffler installed on his person).  

So, you know, in an anecdotal sense, taking antibiotics and feeling better doesn't mean that the antibiotics are the reason that you felt better. It may have something to do with the belief that this doctor cares for me, I'm doing something to help myself, it's very complicated and we don't know all the answers...(Shapiro's rambling and inane commentary was rightfully terminated by the host of the program).  

-Maryland Public Television - Direct Connection - Lyme Disease - Under Our Skin Review - June 27, 2011 
 
 
Carl Tuttle
Independent Researcher
Hudson, NH

---------- Original Message ----------
From: CARL TUTTLE <runagain@comcast.net>
To: "a.robinson@cabi.org" <a.robinson@cabi.org>
Cc: "d.bird@cabi.org" <d.bird@cabi.org>
Date: 09/24/2025 7:14 PM EDT
Subject: Fwd: Managing Lyme in Pregnant and Pediatric Patients 23.25 CME hours of credit (AMA PRA Category 1 and nursing credits available).
 
 
Drs. Robinson and Bird,
 
You might want to consider attending this Scientific Conference because you won't learn anything from theCABI Digital Library and Author: Eugene D. Shapiro's chapter "Lyme Disease in Children" 

The CABI Digital Library is a disgrace!
 
Carl Tuttle

 
---------- Original Message ----------
From: ILADS <conference@ilads.org>
To: runagain@comcast.net
Date: 09/24/2025 5:30 PM EDT
Subject: Managing Lyme in Pregnant and Pediatric Patients
 
Diagnosis and Treatment Strategies in Pregnant and Pediatric Patients (Sponsored by MAPS)
https://www.ilads.org/ilads-conference/2025-ilads-san-antonio-conference/