Help put a stop to unnecessary fluoride fortification of drinking water.
Help put a stop to unnecessary fluoride fortification of drinking water.
The issue
Health and Nutritional Conformity.
Once upon a time in a land far far away; someone once thought that humans were a single species; having identical biochemistry, genomes and nutritional needs and began treating us accordingly.
We now understand that this is not the case. Throughout the World, the evolution of populations differs greatly depending on location, dietary intake and environmental exposure to substances. Together this contributes to subtle differences in the human phenotype through differences in the genome and to gene expression. If we were to taxonomically categorise the human species as we do for bacteria and viruses; we are already many sub-species of homo-sapien and we should therefore be treated accordingly.
On January 5th 1945; Michigan state, United States were the first to introduce fluoride fortification of their town water, other American States and Countries followed shortly after. By 1984, 66% of Australia’s water supply was fluoridated.
At the same time that fluoride fortification was implemented around the World, researchers in India were discovering that natural sources of fluoride in the Indian water supply as low as 1ppm were associated with fluoride toxicity and skeletal fluorosis.
Epigenetic analysis of fluoride toxicity and subsequent fluorosis in genetically susceptible individuals is said to be the result of promoter region DNA hypermethylation and sequential downregulation of expression of genes associated with extracellular matrix deposition and cartilage formation.
The epigenetic effects of fluoride and all other environmental substances are cell-specific. Whilst fluoride may be strengthening tooth enamel, oral consumption may be slowly weakening bones in susceptible populations and individuals.
Nutritional conformity has unpredictable consequences due to many subtle differences in the human genome. Due to rising atmospheric methane, we gain more methylation as we age and our town drinking water may be significantly contributing to weakened skeletal composition in the aging population.
By signing this petition, you are voicing your concern and recognition of the evolutionary differences in populations, where one man’s medicine may be the cause of another’s ailment. You are also requesting that the Food Standards Australia and New Zealand (FSANZ), Health and Medical Research Council and the World Health Organisation (WHO) review the modern evidence pertaining to the cell-specific effects of epigenetics and methylation and reconsider recommendations, and the premature decision of mandatory fortification of drinking water with fluoride.
Genetic heritage should not determine whether you can safely drink the town's water.
For more information pertaining to methylation, fluoride, cell specificity, epigenetics and the damaging effects of nutritional conformity please read the following publication and included references.
Sedley, L Advances in Nutritional Epigenetics—A Fresh Perspective for an Old Idea. Lessons Learned, Limitations, and Future Directions Epigenetics Insights. 2020 www://journals.sagepub.com/doi/full/10.1177/2516865720981924
Image Reference - Vakdevi V, Gopalan V, Arjun L K. Comparison of Fluoride Levels (Total and Extracted) in Young, Old Tea Leaves and Market Tea Samples along with Impact of Tea Infusion on Dental Fluorosis in Fluoride Endemic Villages of Nalgonda District, India. Adv Dent & Oral Health. 2019;10(4): 555793.DOI: 10.19080/ADOH.2019.10.555793
Mitman, G, Murphy, M, Sellers, C. Orisis Landscapes of exposure: knowledge and illness in modern environments. In: Sellers, C, ed. The Artificial Nature of Fluoridated Water: Between Nations, Knowledge and Material Flows. Vol. 2, Issue 19. The University of Chicago Press on Behalf of The History of Science Society; 2004:182-200
Daiwile, AP, Tarale, P, Sivanesan, S, et al. Role of fluoride-induced epigenetic alterations in the development of skeletal fluorosis. Ecotoxicol Environ Saf. 2019;169:410-417. doi:10.1016/j.ecoenv.2018.11.035
For further information please contact me directly EMAIL: lyndasedley@outlook.com
66
The issue
Health and Nutritional Conformity.
Once upon a time in a land far far away; someone once thought that humans were a single species; having identical biochemistry, genomes and nutritional needs and began treating us accordingly.
We now understand that this is not the case. Throughout the World, the evolution of populations differs greatly depending on location, dietary intake and environmental exposure to substances. Together this contributes to subtle differences in the human phenotype through differences in the genome and to gene expression. If we were to taxonomically categorise the human species as we do for bacteria and viruses; we are already many sub-species of homo-sapien and we should therefore be treated accordingly.
On January 5th 1945; Michigan state, United States were the first to introduce fluoride fortification of their town water, other American States and Countries followed shortly after. By 1984, 66% of Australia’s water supply was fluoridated.
At the same time that fluoride fortification was implemented around the World, researchers in India were discovering that natural sources of fluoride in the Indian water supply as low as 1ppm were associated with fluoride toxicity and skeletal fluorosis.
Epigenetic analysis of fluoride toxicity and subsequent fluorosis in genetically susceptible individuals is said to be the result of promoter region DNA hypermethylation and sequential downregulation of expression of genes associated with extracellular matrix deposition and cartilage formation.
The epigenetic effects of fluoride and all other environmental substances are cell-specific. Whilst fluoride may be strengthening tooth enamel, oral consumption may be slowly weakening bones in susceptible populations and individuals.
Nutritional conformity has unpredictable consequences due to many subtle differences in the human genome. Due to rising atmospheric methane, we gain more methylation as we age and our town drinking water may be significantly contributing to weakened skeletal composition in the aging population.
By signing this petition, you are voicing your concern and recognition of the evolutionary differences in populations, where one man’s medicine may be the cause of another’s ailment. You are also requesting that the Food Standards Australia and New Zealand (FSANZ), Health and Medical Research Council and the World Health Organisation (WHO) review the modern evidence pertaining to the cell-specific effects of epigenetics and methylation and reconsider recommendations, and the premature decision of mandatory fortification of drinking water with fluoride.
Genetic heritage should not determine whether you can safely drink the town's water.
For more information pertaining to methylation, fluoride, cell specificity, epigenetics and the damaging effects of nutritional conformity please read the following publication and included references.
Sedley, L Advances in Nutritional Epigenetics—A Fresh Perspective for an Old Idea. Lessons Learned, Limitations, and Future Directions Epigenetics Insights. 2020 www://journals.sagepub.com/doi/full/10.1177/2516865720981924
Image Reference - Vakdevi V, Gopalan V, Arjun L K. Comparison of Fluoride Levels (Total and Extracted) in Young, Old Tea Leaves and Market Tea Samples along with Impact of Tea Infusion on Dental Fluorosis in Fluoride Endemic Villages of Nalgonda District, India. Adv Dent & Oral Health. 2019;10(4): 555793.DOI: 10.19080/ADOH.2019.10.555793
Mitman, G, Murphy, M, Sellers, C. Orisis Landscapes of exposure: knowledge and illness in modern environments. In: Sellers, C, ed. The Artificial Nature of Fluoridated Water: Between Nations, Knowledge and Material Flows. Vol. 2, Issue 19. The University of Chicago Press on Behalf of The History of Science Society; 2004:182-200
Daiwile, AP, Tarale, P, Sivanesan, S, et al. Role of fluoride-induced epigenetic alterations in the development of skeletal fluorosis. Ecotoxicol Environ Saf. 2019;169:410-417. doi:10.1016/j.ecoenv.2018.11.035
For further information please contact me directly EMAIL: lyndasedley@outlook.com
66
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Petition created on 19 December 2020