Lyme denialism reaches new depths……..
Stunning that a medical journal publishes such nonsense without a shred of hard facts to back it up; all propaganda and zero science….
--------- Original Message ----------
From: CARL TUTTLE <runagain@comcast.net>
To: Executivedir@aldf.com, tickbornedisease@hhs.gov
Cc: (84 Undisclosed recipients)
Date: January 15, 2020 at 1:22 PM
Subject: A Review of Antibiotic-Tolerant Persisters and Their Relevance to Post-Treatment Lyme Disease Symptoms
The American Journal of Medicine
A Review of Antibiotic-Tolerant Persisters and Their Relevance to Post-Treatment Lyme Disease Symptoms
https://www.amjmed.com/article/S0002-9343(20)30011-5/fulltext
Jan 15, 2019
American Lyme Disease Foundation,
P.O. Box 466
Lyme, Connecticut 06371
Attn: Phillip J. Baker, PhD. Executive Director
Mr. Baker,
In reference to your recent publication in The American Journal of Medicine, perhaps you could take a moment and explain to the Tick-Borne Disease Working Group why you omitted the following references identifying persistent Lyme disease:
“In 1991 the Lyme disease organism, Borrelia burgdorferi, was grown from the cerebrospinal fluid of my patient Vicki Logan at the Centers for Disease Control in Fort Collins, Colorado despite prior treatment with intravenous antibiotics. Her case made the front page of the New York Times Science Times in August of 1993.” -Kenneth Liegner, MD
2. Vicki Logan’s CDC Fort Collins Positive CSF Culture Report: (My personal Dropbox account)
https://www.dropbox.com/s/vthfdpn7gv8bne2/Logan%20CDC%20Fort%20Collins%20Positive%20CSF%20%20Culture%20Report.JPG?dl=0
Here are links to the seven page autopsy results of patient Vicki Logan showing histopathologic findings consistent with neurologic
manifestations of chronic Lyme disease.
(Vicki Logan’s Autopsy results Page #1, 2, 3, 4, 5, 6, 7)
https://www.dropbox.com/s/xaul84dqmqgbre0/Brenda%20Fitzgerald%20MD%20Director%20CDC.docx?dl=0
The destructive nature of Borrelia is evident in Vicki Logan’s liver (nutmeg liver), kidneys, heart, lungs and brain. The patient died after the insurer refused additional IV antibiotic therapy
3. Persistent Borrelia Infection in Patients with Ongoing Symptoms of Lyme Disease
Published: 14 April 2018
http://www.mdpi.com/2227-9032/6/2/33
All of these patients were culture positive for infection (genital secretions, skin and blood) even after multiple years on antibiotics so there was no relief from current antimicrobials. Some of these patients had taken as many as eleven different types of antibiotics.
I would like to point out the following 1995 case study from Stony Brook Lyme Clinic.
I understand the patient received thirteen spinal taps, multiple courses of IV and oral meds, and relapsed after each one, proven by CSF antigens and/or PCR. The only way this patient (said to be a physician) remained in remission was to keep her on open ended clarithromycin- was on it for 22 months by the time of publication.
4. Seronegative Chronic Relapsing Neuroborreliosis.
https://www.ncbi.nlm.nih.gov/pubmed/7796837
Lawrence C.a · Lipton R.B.b · Lowy F.D.c · Coyle P.K.d
aDepartment of Medicine, bDepartment of Neurology, and cDivision of Infectious Diseases, Albert Einstein College of Medicine, and dDepartment of Neurology, State University of New York at Stony Brook, New York, NY., USA
Eur Neurol 1995; 35:113–117 (DOI:10.1159/000117104)
Abstract
We report an unusual patient with evidence of Borrelia burgdorferi infection who experienced repeated neurologic relapses despite aggressive antibiotic therapy. Each course of therapy was associated with a Jarisch-Herxheimer-like reaction. Although the patient never had detectable free antibodies to B. burgdorferi in serum or spinal fluid, the CSF was positive on multiple occasions for complexed anti-B. burgdorferi antibodies, B. burgdorferi nucleic acids and free antigen.
________________________
This is not the only case where a negative antibody response was identified. In fact I have attached the following document referencing:
5. Seronegativity in Lyme borreliosis and Other Spirochetal Infections
https://www.dropbox.com/s/3d6m45jzlhhwalu/Seronegativity.pdf?dl=0
“If false results are to be feared, it is the false negative result which holds the greatest peril for the patient.”
6. Peer Reviewed Evidence of Persistence of Lyme Disease Spirochete Borrelia burgdorferi and Tick-Borne Diseases (700 arrticles)
https://www.dropbox.com/s/14kogblsjc7po2x/EvidenceofPersistence-V2.pdf?dl=0
Question Mr. Baker….. What is the motivation for suppressing evidence of persistent infection dating back to the 10 years you spent as the Lyme Disease Program Officer for the NIH?
Carl Tuttle
Lyme Endemic Hudson, NH
Cc: The Tick-Borne Disease Working Group
Kumsal Bayazit, Chief Executive Officer of Elsevier
Additional relevant references:
The statement below was extracted from Dr. Raymond Dattwyler’s patent:
1. United States Patent US 7.887,815 B2
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=7,887,815.PN.&OS=PN/7,887,815&RS=PN/7,887,815
Dattwyler et al. Feb. 15, 2011
“Clinically, Lyme disease is a progressive disease with a wide array of manifestations. Early diagnosis and treatment is critical to prevent progression. Late disseminated infection can be associated with permanent damage to the nervous and musculoskeletal systems.”
2. Congenital Transmission of Lyme Disease (28 references)
https://www.dropbox.com/s/xlju8w25phkypy0/Congenital%20Transmission%20of%20Lyme.pdf?dl=0
3. Deaths from Lyme Disease
https://www.dropbox.com/s/eo794dx7zspc1ln/Ld%20deaths.doc?dl=0
In Scientific Literature, Books, Newsletters/Newspapers/Obituary
Compiled by: John D. Scott, Research Scientist 17 April 2018