Please see the message below addressed to the New York Medical College Student Senate. Student profiles are public information and can be accessed at the following link: https://www.nymc.edu/current-students/student-life/student-organizations/student-government/som-student-senate/members/ Consider writing your own letter of concern over the mishandling of Lyme disease by New York Medical College and the hardship this has caused for you or your loved ones. -Carl Tuttle Letter to NYMC Student Senate: ________________________________________ From: "Carl Tuttle" To: "lydia bunker" Cc: "mario corro" , "qais karim" , "anna odermann" , "jessica oh" , "jacob feldman" , "adam gordon" , "seung jeong" , "stephen shapero" , "kaitlin swanson" , "bevan bonhomme" , "hannah gissel" , "philip maynard" , "alexander selby" , "justin cole" , "kenny guber" , "robert kane" , "jennifer lindelof" , "abhiniti mittal" , "kendall presti" Sent: Friday, April 7, 2017 9:48:41 AM Subject: Fwd: Letters to Joseph Alpert, MD, Editor-in-Chief of The American Journal of Medicine April 7, 2017 New York Medical College 40 Sunshine Cottage RD Valhalla, NY 10595 Attn: Student Senate To: Lydia Bunker, President of the Student Senate 2016-2017 academic year In the not too distant future there will be a global inquiry into the mishandling of a disease here in the United States with the focus on New York Medical College, specifically; Professor Gary Wormser. We are dealing with a life-altering/life-threatening infection misclassified as a simple nuisance disease as this antibiotic resistant/tolerant superbug infects over 300,000 annually; an infection rate six times the AIDS epidemic and twice as prevalent as breast cancer. Wormser’s selective use of literature citing studies supporting his viewpoint ignores multiple studies that challenge his simplistic position. We are experiencing a runaway epidemic here in the United States with unacceptable testing, inadequate treatment, lack of medical training and absolutely no disease control. The patient experience with this disease does not resemble the established disease definition (Wormser’s definition) as the destructive nature is seen in histopathologic findings of the autopsy results provided in the letter below. Please take a moment to read the following letters (AND REFERENCES/ATTACHMENTS) to Joseph Alpert, MD, Editor-in-Chief, of The American Journal of Medicine as it outlines a crime to humanity perpetuated by New York Medical College. The college you have paid good money to receive your medical degree. Will you sit back and ignore what you are about to read or will you challenge what has been wrongfully established before you leave New York Medical College? The mishandling of this disease is the most shameful affair in the history of medicine. Your degree will remind you of this for the rest of your career. Respectfully submitted, Carl Tuttle Hudson, NH 1st letter to Joseph Alpert, MD, Editor-in-Chief, of The American Journal of Medicine: ________________________________________ From: "Carl Tuttle" To: jalpert@email.arizona.edu Cc: complaints@scipub.org, editors@amjmed.org, jdalen@email.arizona.edu, hellmann@jhmi.edu, kraftm@email.arizona.edu, cwiener@jhmi.edu, schipkin@kin.umass.edu, aamin@lifespan.org, "Arti Shukla" , chibun-chan@ouhsc.edu, drbanik@umn.edu, enicklet@umich.edu, E-Booms@NEIU.edu, jxu@nmsu.edu, "lei sun" , "Myunghan Choi" , xi@health.southalabama.edu, "d w wilson" , "v thijssen" , jiannjou@csmu.edu.tw, pablocotosegura@gmail.com, "bulls threepeat" , stanta@icgeb.org, "paolo ascierto" , giannouk@med.uth.gr, "utz krug" , massoudtoussi@gmail.com, spss2005@126.com, orsinimarco@hotmail.com, "a raikos" , executivedir@aldf.com, gwormser@nymc.edu, "eugene shapiro" , "sten vermund" Sent: Saturday, March 4, 2017 3:23:49 PM Subject: False and Misleading Information about Lyme Disease False and Misleading Information about Lyme Disease Eugene D. Shapiro, M.D., Phillip J. Baker, Ph.D., Executive Director, Gary P. Wormser, http://www.amjmed.com/article/S0002-9343(17)30138-9/pdf March 4, 2017 The American Journal of Medicine 3615 N. Prince Village Place, Suite 181 Tucson, Arizona 85719 Attn: Editorial Board To the Editors of The American Journal of Medicine, Lyme disease is capable of producing sudden death with no warning signs; [1,2,3,] heart damage requiring transplant, [4] paralysis with seizures, [5] Lymphoma [6] and persistent infection after antibiotic treatment [7, 8,9,10,11] along with congenital transmission [12] and ability to create wheelchair bound patients [13]. The last time we recognized a disease with this potential to cause serious harm, (Zika) the CDC wanted 1.8 billion for research. [14] The authors of this manuscript have compared Lyme disease to the aches and pains of daily living. There are no Public Service Announcements informing the general public that you could become horribly disabled from Lyme disease. Quote from Senator Richard Blumenthal: "Today for me culminates more than a decade of work and probably a decade more, because I've seen firsthand the devastating, absolutely unacceptable damage done by Lyme disease to individual human beings, Connecticut children and residents whose lives have been changed forever as a result of Lyme disease” Source: http://ctmirror.org/2011/07/18/blumenthal-takes-lyme-disease-fight-senate/ In regards to laboratory testing, please see the following quote from Dr. Kenneth Liegner: “In 1991 the Lyme disease organism, Borrelia burgdorferi, was grown from the cerebrospinal fluid of my patient Vicki Logan at the Centers for Disease Control in Fort Collins, Colorado despite prior treatment with intravenous antibiotics. Her case made the front page of the New York Times Science Times in August of 1993.” -Kenneth Liegner, MD Source: http://cognitiveliberty.net/wp-content/uploads/2014/12/David-Dennis.pdf Vicki Logan’s CDC Fort Collins Positive CSF Culture Report: (My personal Dropbox account) https://www.dropbox.com/s/vthfdpn7gv8bne2/Logan%20CDC%20Fort%20Collins%20Positive%20CSF%20%20Culture%20Report.JPG?dl=0 What we are dealing with here is an antibiotic resistant/tolerant superbug but the focus over the past three decades (as seen once again in the Shapiro article) has been to discredit the sick and disabled along with the practitioners attempting to help these patients as opposed to finding new antimicrobials effective in eradicating all forms of the Borrelia spirochete; L-forms, round bodies and persister cells. [15] Shapiro and colleagues claim that: “Lyme disease patients who have been infected by B. burgdorferi for many weeks or months are almost invariably seropositive by 2-tier tests.” Please see the following letter (And attachments) addressed to the World Health Organization regarding faulty/misleading antibody tests for Lyme disease. 11th email to the World Health Organization: ________________________________________ From: "Carl Tuttle" To: smithi@who.int Cc: briands@who.int, engelsd@who.int, renm@who.int, aylwardb@who.int Sent: Monday, August 1, 2016 10:35:18 AM Subject: Dr. Sam Donta's Clinical Notes August 1, 2016 World Health Organization Avenue Appia 20 1211 Geneva 27 Switzerland Attn: Ian Smith MD, Executive Director of the Director-General's Office Dear Dr. Smith, Dr. Sam Donta spent a career studying Lyme disease as a professor of medicine and Director of the Boston University Medical Campus Lyme Disease Center. I have attached a copy of his clinical notes in reference to my personal case of Lyme disease. I would like to call attention to the Western blot lab results reported in his clinical notes. Positive results here in the United States require specific bands; two out of three IgM and five of ten IgG. In contrast, China’s Western blot requires a single band (Band 41) for positive results: A Study of the Technique of Western Blot for Diagnosis of Lyme Disease caused by Borrelia afzelii in China* 2013 Mar;26(3):190-200. doi: 10.3967/0895-3988.2013.03.006. http://www.ncbi.nlm.nih.gov/pubmed/23425802 Band 41 as you know represents the antibody against the spirochete’s flagella. There are other spirochetal infections that might produce a positive response to band 41; Syphilis (Treponema pallidum) and periodontal pathogen spirochetes (Treponema denticola). These “other” spirochetes can be easily ruled out if there is a question of false positive Lyme results. Dr. Donta has seen all family members in our household as we were all horribly sick living in this Lyme endemic region of New England. None of us tested positive for Lyme disease following the CDC’s strict criteria for positive lab test results. I have attached a copy of my wife’s Western blot for your review. My wife by the way could barely walk up a flight of stairs without excruciating knee pain and we thought she might require knee replacement surgery. I’m happy to report that my wife’s knee pain has resolved completely after long term antibiotics of three year’s duration. The point I would like to convey here is that had we not seen Dr. Donta, none of us would have been treated. This is not an isolated example! Thousands upon thousands of suffering Lyme patients are told they do not have Lyme disease and are not treated as a result of the strict testing criteria. In addition to the strict test criteria, bands 31 and 34 were removed from the Western blot to facilitate vaccine development. Bands 31 (Outer surface protein A) and 34 (Outer surface protein B) are highly specific to Borrelia so a positive result to either of these two bands confirms infection yet the two most important indicators of infection are no longer offered through standard commercial tests. The human Lyme vaccine was a failure while the two most significant Western blot bands have not been restored. Int J Risk Saf Med. 2011;23(2):89-96. doi: 10.3233/JRS-2011-0527. Neurological complications of vaccination with outer surface protein A (OspA). Marks DH1. http://www.ncbi.nlm.nih.gov/pubmed/21673416 Dr. David Volkman (Lyme researcher) wrote a letter to Dr. Tom Frieden, Director of the CDC asking that the strict criteria for positive results be reevaluated. I have attached a copy of Dr. Volkman’s letter to this email. Dr. Volkman did not receive a response from the CDC. “One way to stop an epidemic is to redefine it by narrowing the disease's diagnostic criteria so tightly that it's hard for any chronically ill Lyme patient to fit the profile and obtain insurance reimbursement.” Dr Smith, I ask the following questions, “How long do we continue to turn a blind eye to the mishandling of Lyme disease here in the United States? Does the World Health Organization have any authority in questioning what has been wrongly established?” A response to this inquiry is requested. Sincerely, Carl Tuttle Hudson, NH Lyme Disease: Call for a “Manhattan Project” to Combat the Epidemic Raphael B. Stricker and Lorraine Johnson http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879353/ Attachments: Dr. Volkman’s letter to the CDC https://www.dropbox.com/s/sl5x3gzguowpj6n/Volkman%20letter%20to%20Frieden.doc?dl=0 Western blot lab test results https://www.dropbox.com/s/ppus0unm0j2oiff/Western%20Blot.pdf?dl=0 _________________ In summary: Lyme disease belongs in the same health threat category as AIDS, Zika and Ebloa but a handful of academics have controlled the narrative for the past three decades through editorial censorship and colluded to deny this life-altering/life-threatening infection by promoting an outdated simplistic viewpoint of a disease capable of ruining lives. We are experiencing a runaway plague with unacceptable testing, inadequate treatment, lack of medical training and absolutely no disease control. Those who have perpetuated this thirty year dogma (along with the editors who publish their propaganda) are responsible for the most shameful affair in the history of medicine. The mishandling of Lyme disease is a crime against humanity on a global scale. Sincerely, Carl Tuttle Hudson, NH REFERENCES: 1. Cardiac Tropism of Borrelia burgdorferi: An Autopsy Study of Sudden Cardiac Death Associated with Lyme Carditis. (March 2016) http://ajp.amjpathol.org/article/S0002-9440(16)00099-7/abstract Excerpt: “Fatal Lyme carditis caused by the spirochete Borrelia burgdorferi rarely is identified. Here, we describe the pathologic, immunohistochemical, and molecular findings of five case patients.” 2. CDC Case Study #1: Three Sudden Cardiac Deaths Associated with Lyme Carditis: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6249a1.htm?s_cid=mm6249a1_w 3. CDC Case Study #2: A case report of a 17-year old male with fatal Lyme carditis http://www.cardiovascularpathology.com/article/S1054-8807(15)00025-3/abstract?rss=yes 4. Professor Neil Spector: Duke physician uses near-death experience to encourage patient self-advocacy http://www.dukechronicle.com/articles/2015/05/28/duke-physician-uses-near-death-experience-encourage-patient-self-advocacy#.VYlYnxtViko Dr Neil Spector from Duke University required a heart transplant after his Lyme disease went undiagnosed for four years. 5. Nashua Mom in the 'Lyme Light' on Katie Couric Show http://patch.com/new-hampshire/nashua/nashua-mom-talks-chronic-lyme-on-katie-couric-show Fifth-grade teacher Kelly Downing was paralyzed from the neck down and interviewed by Katie Couric. 6. Infection by Borrelia burgdorferi and cutaneous B-cell lymphoma (Cancer) https://www.ncbi.nlm.nih.gov/pubmed/9331890 Specific DNA sequences of Borrelia burgdorferi were identified in cutaneous lesions from 9 patients (follicle center lymphoma: 3/20; immunocytoma: 3/4; marginal zone B-cell lymphoma: 2/20; diffuse large B-cell lymphoma: 1/6). 7. Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis. http://translational-medicine.biomedcentral.com/articles/10.1186/s12967-015-0701-z 41 of 100 patients under surveillance for persistent LB in an endemic area were positive for urinary OspA protein after antibiotic treatment. 8. Culture evidence of Lyme disease in antibiotic treated patients living in the Southeast. http://danielcameronmd.com/culture-evidence-of-lyme-disease-in-antibiotic-treated-patients-living-in-the-southeast/ Rudenko and colleagues reported culture confirmation of chronic Lyme disease in 24 patients in North Carolina, Florida, and Georgia. All had undergone previous antibiotic treatment. 9. DNA sequencing diagnosis of off-season spirochetemia with low bacterial density in Borrelia burgdorferi and Borrelia miyamotoi infections. https://www.ncbi.nlm.nih.gov/pubmed/24968274 Faulty/misleading antibody tests landed a sixteen year old male in a psychiatric ward when his lab results did not meet the CDC’s strict criteria for positive results. His Western blot had only four of the required five IgG bands. Subsequent DNA sequencing identified a spirochetemia in this patient’s blood so his psychiatric issues were a result of neurologic Lyme disease misdiagnosed by antiquated/misleading serology. This patient was previously treated with antibiotics. 10. Granulomatous hepatitis associated with chronic Borrelia burgdorferi infection: a case report http://www.labome.org/research/Granulomatous-hepatitis-associated-with-chronic-Borrelia-burgdorferi-infection-a-case-report.html The patient had active, systemic Borrelia burgdorferi infection and consequent Lyme hepatitis, despite antibiotic therapy. 11. Scotty Shelton and Persistent Infection in Saginaw MN https://www.change.org/p/the-us-senate-calling-for-a-congressional-investigation-of-the-cdc-idsa-and-aldf/u/11685820 “Scotty's brain (cerebral cortex) was positive for Borrelia burgdorferi and Borrelia myamotoi, his testicle is positive for Bb. We are now testing other tissues. Seven years of antibiotics and 3.5 years of natural treatments (along with antibiotics) and he was highly highly positive.” 12. Congenital Transmission of Lyme/TBD https://www.dropbox.com/s/z10em0szgpm8bll/Congenital%20Transmission%20of%20Lyme%202015.doc?dl=0 13. Wheelchair-Bound Girl Calls Blessing By Pope Francis ‘Most Precious Moment Of My Life’http://newyork.cbslocal.com/2015/09/24/pope-francis-blesses-girl-in-wheelchair/ NEW YORK (CBSNewYork) — A 12-year-old girl who has been confined to a wheelchair since being diagnosed with Lyme disease said meeting Pope Francis as he arrived in New York Thursday was “the most precious moment of my life.” 14. $1.8 billion to fight Zika: CDC moves to highest alert level https://www.washingtonpost.com/news/post-politics/wp/2016/02/08/obama-to-ask-congress-for-1-8-billion-to-combat-zika-virus/ 15. LYME SCI: Why persister cells matter with Lyme disease https://www.lymedisease.org/lyme-sci-why-persister-cells-matter-with-lyme-disease/ 2nd letter to Joseph Alpert, MD, Editor-in-Chief, of The American Journal of Medicine: ________________________________________ From: "Carl Tuttle" To: jalpert@email.arizona.edu Cc: complaints@scipub.org, editors@amjmed.org, jdalen@email.arizona.edu, hellmann@jhmi.edu, kraftm@email.arizona.edu, cwiener@jhmi.edu, schipkin@kin.umass.edu, aamin@lifespan.org, "Arti Shukla" , chibun-chan@ouhsc.edu, drbanik@umn.edu, enicklet@umich.edu, E-Booms@NEIU.edu, jxu@nmsu.edu, "lei sun" , "Myunghan Choi" , xi@health.southalabama.edu, "d w wilson" , "v thijssen" , jiannjou@csmu.edu.tw, pablocotosegura@gmail.com, "bulls threepeat" , stanta@icgeb.org, "paolo ascierto" , giannouk@med.uth.gr, "utz krug" , massoudtoussi@gmail.com, spss2005@126.com, orsinimarco@hotmail.com, "a raikos" , executivedir@aldf.com, gwormser@nymc.edu, "eugene shapiro" , "sten vermund" Sent: Tuesday, March 7, 2017 11:14:04 AM Subject: Re: False and Misleading Information about Lyme Disease March 7, 2017 The American Journal of Medicine 3615 N. Prince Village Place, Suite 181 Tucson, Arizona 85719 Attn: Joseph Alpert, MD, Editor in Chief Dear Dr. Alpert, As a follow-up to my previous letter dated March 4th, Lyme patient Vicki Logan’s 1991 positive culture test performed by the Centers for Disease Control should have set off a red flag but was ignored while the focus remained on discrediting the sick and disabled Lyme patient population. [1] Here are links to the seven page autopsy results of patient Vicky Logan showing histopathologic findings consistent with neurologic manifestations of chronic Lyme disease. (Vicky Logan’s Autopsy results Page #1, 2, 3, 4, 5, 6, 7) The destructive nature of Borrelia is evident in Vicky Logan’s liver (nutmeg liver), kidneys, heart, lungs and brain. The patient died after the insurer refused additional IV antibiotic therapy. I would like to point out the following case study from Stony Brook Lyme clinic. I understand the patient received thirteen spinal taps, multiple courses of IV and oral meds, and relapsed after each one, proven by CSF antigens and/or PCR. The only way this patient (said to be a physician) remained in remission was to keep her on open ended clarithromycin- was on it for 22 months by the time of publication. Seronegative Chronic Relapsing Neuroborreliosis. https://www.ncbi.nlm.nih.gov/pubmed/7796837 Lawrence C.a · Lipton R.B.b · Lowy F.D.c · Coyle P.K.d aDepartment of Medicine, bDepartment of Neurology, and cDivision of Infectious Diseases, Albert Einstein College of Medicine, and dDepartment of Neurology, State University of New York at Stony Brook, New York, NY., USA Eur Neurol 1995; 35:113–117 (DOI:10.1159/000117104) Abstract We report an unusual patient with evidence of Borrelia burgdorferi infection who experienced repeated neurologic relapses despite aggressive antibiotic therapy. Each course of therapy was associated with a Jarisch-Herxheimer-like reaction. Although the patient never had detectable free antibodies to B. burgdorferi in serum or spinal fluid, the CSF was positive on multiple occasions for complexed anti-B. burgdorferi antibodies, B. burgdorferi nucleic acids and free antigen. ________________________ For the past three decades, Lyme disease has been portrayed as hard to catch and easily treated [2] while those who control the narrative (Through editorial censorship) refuse to recognize this pathogen as an antibiotic resistant/tolerant superbug by suppressing evidence of persistent infection. [3] This misclassification has all but eliminated government funding that should have been equal to or greater than AIDS or Zika which are also life-altering/life-threatening infections in need of cures. It is believed that Lyme disease was pigeonholed into its current status by the two principal investigators of the previous Lyme disease vaccines; SmithKlineBeecham's LymeRix and Connaught's vaccine (which never made it to market) as these investigators conceptualized a disease that would enable vaccine development. A preventive vaccine for Lyme disease would not satisfy the FDA if a chronic persistent infection and seronegative disease exist. The lead author of the one-size-fits-all Lyme treatment guideline (which matches the conceptualized disease) was the principle investigator of Connaught's Lyme vaccine, Dr Gary Wormser. This is a flagrant conflict of interest. Have we been dealing with an antibiotic resistant superbug purposely concealed to promote vaccine development? Philip Baker of the American Lyme Disease Foundation, Gary Wormser of New York Medical College and Eugene Shapiro of Yale School of Medicine are all responsible for the death of Lyme patient Vicky Logan and those who took their own lives when the horror of Lyme could no longer be tolerated. Responsibility squarely lies in the editors who publish the bias papers of those who continue to suppress evidence of persistent infection. The mishandling of Lyme disease is blatantly obvious. -Carl Tuttle Hudson, NH REFERENCES: ________________________________________ [1] Lyme disease antiscience http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(12)70054-3/fulltext [2] Lyme Disease Is Hard to Catch And Easy to Halt, Study Finds New York Times By GINA KOLATA Published: June 13, 2001 http://www.nytimes.com/2001/06/13/us/lyme-disease-is-hard-to-catch-and-easy-to-halt-study-finds.html Excerpt: But some who have treated hundreds of patients with long-term antibiotics, like Dr. Sam L. Donta of Boston University Medical Center, were not convinced. The antibiotics in the studies were not given for a long enough time, Dr. Donta said, and he would have chosen different ones. Perhaps all that the studies show, he said, is ''that this particular treatment doesn't work.'' [3] Peer Reviewed Evidence of Persistence of Lyme Disease Spirochete Borrelia burgdorferi and Tick-Borne Diseases after the mandated one-size-fits-all IDSA treatment approach: (700 articles) http://www.ilads.org/ilads_news/wp-content/uploads/2015/09/EvidenceofPersistence-V2.pdf