Letter to Dr Mark Klempner with Cc: to senior leadership members of UMass Medical School…….. ________________________________________ From: "Carl Tuttle" To: "Mark Klempner" , "marie szaniszlo" Cc: "Michael Collins" , "Deborah Molrine" , "Sadettin Ozturk" , "Keith Reimann" Sent: Friday, October 23, 2015 9:29:20 AM Subject: UMass works toward new Lyme injection UMass works toward new Lyme injection Would stop disease Marie Szaniszlo Friday, October 09, 2015 http://www.bostonherald.com/business/healthcare/2015/10/umass_works_toward_new_lyme_injection “…the antibody would kill the bacteria in the tick’s gut, before the bacteria could move into the salivary glands and be transmitted to the mouse through a bite.” Oct 23, 2015 Mark S. Klempner, MD Executive Vice Chancellor-MassBiologics Professor of Medicine University of Massachusetts Medical School 460 Walk Hill Street Boston, MA 02126 Dear Dr Klempner, Dr. Willy Burgdorfer (discoverer of the Borrelia burgdorferi spirochete) was quoted during a conference at Bard College in 1999 stating that about 5-10% of ticks that are carrying Lyme disease have a systemic infection and have the disease in their saliva and can transmit it as soon as they bite. He said, “There is no safety window.” How will your Lyme PrEP antibody vaccine protect humans in this scenario? Might your vaccine promote a false sense of security? Certainly there will be no protection from transmission of Borrelia burgdorferi by blood transfusion: (We don’t screen our blood supply for Lyme disease) http://lymerick.net/Transmission-Bb-transfusion.htm And finally how would the Lyme PrEP antibody vaccine protect the patient in the case of transmission by contact via feces, urine or tick-excretes? http://lymerick.net/Transmission-Bb-contact.htm Perhaps a disclaimer will be required to inform the patient (informed consent) that the vaccine does not provide protection via the following transmission routes: 1. Ticks that are carrying Lyme disease with a systemic infection and have the disease in their saliva. 2. Transmission of Borrelia burgdorferi through blood transfusion. 3. Congenital transmission. 28 Peer-Reviewed Studies http://home.comcast.net/~runagain/Congenital%20Transmission%20of%20Lyme.doc 4. Transmission by contact via feces, urine or tick-excretes. 5. Sexual transmission of Lyme disease. (This route of transmission will be proven in the not to distant future) Sincerely, Carl Tuttle Hudson, NH