The London mayor conceded councils might need to 'tweak' LTNs or scrap them - but he defended efforts to reduce congestion and pollution.
The Government pursued a growth of LTNs in the wake of the Covid pandemic in 2020 as it sought to encourage more people to walk or cycle in towns and cities.
But they have proved unpopular with drivers and residents, with many instances of road bollards being vandalised, for forcing them away from their usual routes.
There are concerns that LTNs have merely moved congestion and pollution to other roads.
Ministers have also been accused of 'greenwashing' by campaigners after it was revealed the Department for Transport (DfT) could give no evidence that LTNs reduce the number of miles driven.
Sadiq Khan admitted some low-traffic neighbourhoods in London 'aren't perfect' and may need removing amid a backlash against the controversial schemes.
The Government pursued a growth of LTNs in the wake of the Covid pandemic in 2020 as it sought to encourage more people to walk or cycle in towns and cities.
But LTNs have proved unpopular with drivers and local residents. There are concerns they have merely moved congestion from some parts of towns and cities to other roads.
More than a quarter of LTNs have been scrapped since being installed after the outbreak of the Covid pandemic, an analysis has shown.
The i newspaper reported it had asked regional transport authorities and local councils in Britain's main urban areas to provide data on the number of experimental LTNs installed - and scrapped - since March 2020.
The responses, received last year, covered 105 local authorities and showed that in these areas 189 LTNs were installed since March 2020 and 52 (28 per cent) have since been removed.