There's no end to the franchise that introduced the world to computer animation in 1995, of which will most likely not be over until there's been a film that flops. This year came Toy Story 5 which only the second theatrically released film installment to an animated film franchise of all time, and the first one to do well at the box office, meaning that there's a future for the franchise, although some film franchises that ended due to their being an unsuccessful film such as the Ice Age films are in for comebacks. 

In terms of if ever we'll be in for a Toy Story 6, we'll for certain if there's an announcement going by the end of 2030, going back how the 4th and 5th films were announced in the years that the previous films had their 4 year anniversaries. Oh and Kenna Harris who co-directed Toy Story 5 should be the main director of the 6th film, similar to how Lee Unkrich was the main director of Toy Story 3 after co-directing the 2nd film, which shouldn't be a problem provided said film does not go through production issues to point of eventually changing the main director like Toy Story 4 had done. Of course there is so much more we would like to know with the world of toys coming to life, for instance on if this also applies to lawn ornaments and statues, and what we see with toys at particular sorts of places that we haven't seen before, and to see how things are with toys who are outdated with how they appear, and how things are with toys from discontinued toy lines, along with other issues the series could maybe tackle with what toys have been known to go through.

Plus there are some moments in the Toy Story series that people have longed for which Toy Story 5 still has not accomplished, which includes villains from previous films making a comeback, for instance with Stinky Pete the Prospector and Lotso who could team up, in addition to Al McWiggin with whatever he got up to after the events of Toy Story 2 which is certainly not working at the place Lillypad was made. Although some of these could be accomplished in shorts and tv specials, for instance with a special serving as a prequel showing what happened after the events of the first film with Sid Phillips being the only human to have ever seen toys come to life to point of fearing them, especially with showing Toy Story 3 through his perspective as the garbage man, it might actually be thanks to him that the squeeze toy aliens were able to get to the crane that would save the toys from being incinerated in that infamous scene.