Please see the following Huffington Post article: Flunk the Lyme test? Just wait and get sicker http://www.huffingtonpost.com/entry/5873ef2fe4b08052400ee537?timestamp=1483994986602 By Mary Beth Pfeiffer Jan 9, 2017 Second letter to Frieden regarding faulty/misleading antibody tests for Lyme disease with Cc: to legislators on three continents involved in Lyme disease: ________________________________________ From: "Carl Tuttle" To: "txf2" Cc: "CDCExecSec" , "coh2" , acs1@cdc.gov, editor@PainNewsNetwork.org, chanm@who.int, aylwardb@who.int, renm@who.int, engelsd@who.int, briands@who.int, jfacar7@hotmail.com, "antoine andremont" , "Peter Collignon" , "John conly" , pidonado@corpoica.org.co, pjcray@ncsu.edu, galasmf@yahoo.com.ar, rshe@food.dtu.dk, "Rebecca irwin" , maislam@icddrb.org, skariuki@kemri.org, hyosun610@gmail.com, smcewen@uoguelph.ca, "gerard moulin" , "arno muller pro" , antongandjio@yahoo.fr, "patrick otto" , ranjithdpperera@hotmail.com, flaviarossi61@gmail.com, hmscott@cvm.tamu.edu, "j wagenaar" , "HendrikJan Ormel" , "e erlacher-vindel" , gmatar@aub.edu.lb, aidarakanea@who.int, mumforde@who.int, pereze@pan.ops-oms.org, seoy@who.int, "Ian Michael SMITH" , "Minister Ley" , "veronica hughes" , "christopher whitty" , "Dick Blumenthal" , huntj@parliament.uk, "senator madigan" , "Countess MAR" , "Cara Osborn" , "Peter Clark" , "eric waskowicz" , "Serino" , bonacic@senate.state.ny.us, "Kemp Hannon" , asamoa-baaha@who.int, bustreof@who.int, chestnovo@who.int, fukudak@who.int, inoueh@who.int, kienym@who.int, minghuir@who.int, troedssonh@who.int, ramanan@cddep.org Sent: Monday, January 9, 2017 8:26:17 AM Subject: Dr. David Volkman’s letter sent to Dr. Thomas Frieden, Director of the CDC Jan 9, 2017 Centers for Disease Control 1600 Clifton Road Atlanta, GA 30329-4027 Attn: Dr. Tom Frieden, Director Dr. Frieden, Before you leave office on the 20th of January perhaps you could explain why you refused to respond to Dr. David Volkman’s letter regarding the reevaluation of the CDC’s strict criteria for positive Lyme disease test results. (See attachment) https://www.dropbox.com/s/sl5x3gzguowpj6n/Volkman%20letter%20to%20Frieden.doc?dl=0 The letter below addressed to the WHO’s Ian Smith MD, Executive Director of the Director-General's Office describes the difficulty in obtaining a diagnosis due to the strict testing criteria. Please Reply to All as everyone is interested in your response to this serious concern as it relates to a life-altering/life threatening infection. Carl Tuttle Hudson, NH USA Definition of accountability: An obligation or willingness to accept responsibility or to account for one's actions. Source: https://www.merriam-webster.com/dictionary/accountability 11th email to the World Health Organization: ________________________________________ From: "Carl Tuttle" To: smithi@who.int Cc: briands@who.int, engelsd@who.int, renm@who.int, aylwardb@who.int Sent: Monday, August 1, 2016 10:35:18 AM Subject: Dr. Sam Donta's Clinical Notes August 1, 2016 World Health Organization Avenue Appia 20 1211 Geneva 27 Switzerland Attn: Ian Smith MD, Executive Director of the Director-General's Office Dear Dr. Smith, Dr. Sam Donta spent a career studying Lyme disease as a professor of medicine and Director of the Boston University Medical Campus Lyme Disease Center. I have attached a copy of his clinical notes in reference to my personal case of Lyme disease. I would like to call attention to the Western blot lab results reported in his clinical notes. Positive results here in the United States require specific bands; two out of three IgM and five of ten IgG. In contrast, China’s Western blot requires a single band (Band 41) for positive results: A Study of the Technique of Western Blot for Diagnosis of Lyme Disease caused by Borrelia afzelii in China* 2013 Mar;26(3):190-200. doi: 10.3967/0895-3988.2013.03.006. http://www.ncbi.nlm.nih.gov/pubmed/23425802 Band 41 as you know represents the antibody against the spirochete’s flagella. There are other spirochetal infections that might produce a positive response to band 41; Syphilis (Treponema pallidum) and periodontal pathogen spirochetes (Treponema denticola). These “other” spirochetes can be easily ruled out if there is a question of false positive Lyme results. Dr. Donta has seen all family members in our household as we were all horribly sick living in this Lyme endemic region of New England. None of us tested positive for Lyme disease following the CDC’s strict criteria for positive lab test results. I have attached a copy of my wife’s Western blot for your review. https://www.dropbox.com/s/ppus0unm0j2oiff/Western%20Blot.pdf?dl=0 My wife by the way could barely walk up a flight of stairs without excruciating knee pain and we thought she might require knee replacement surgery. I’m happy to report that my wife’s knee pain has resolved completely after long term antibiotics of three year’s duration. The point I would like to convey here is that had we not seen Dr. Donta, none of us would have been treated. This is not an isolated example! Thousands upon thousands of suffering Lyme patients are told they do not have Lyme disease and are not treated as a result of the strict testing criteria. In addition to the strict test criteria, bands 31 and 34 were removed from the Western blot to facilitate vaccine development. Bands 31 (Outer surface protein A) and 34 (Outer surface protein B) are highly specific to Borrelia so a positive result to either of these two bands confirms infection yet the two most important indicators of infection are no longer offered through standard commercial tests. The human Lyme vaccine was a failure while the two most significant Western blot bands have not been restored. Int J Risk Saf Med. 2011;23(2):89-96. doi: 10.3233/JRS-2011-0527. Neurological complications of vaccination with outer surface protein A (OspA). Marks DH1. http://www.ncbi.nlm.nih.gov/pubmed/21673416 Dr. David Volkman (Lyme researcher) wrote a letter to Dr. Tom Frieden, Director of the CDC asking that the strict criteria for positive results be reevaluated. I have attached a copy of Dr. Volkman’s letter to this email. Dr. Volkman did not receive a response from the CDC. https://www.dropbox.com/s/sl5x3gzguowpj6n/Volkman%20letter%20to%20Frieden.doc?dl=0 “One way to stop an epidemic is to redefine it by narrowing the disease's diagnostic criteria so tightly that it's hard for any chronically ill Lyme patient to fit the profile and obtain insurance reimbursement.” Dr Smith, I ask the following questions, “How long do we continue to turn a blind eye to the mishandling of Lyme disease here in the United States? Does the World Health Organization have any authority in questioning what has been wrongly established?” A response to this inquiry is requested. Sincerely, Carl Tuttle Hudson, NH Lyme Disease: Call for a “Manhattan Project” to Combat the Epidemic Raphael B. Stricker and Lorraine Johnson http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879353/