As much as it would be nice to have done in the hands of Disney, it’s best to keep in mind how the cast members have aged since 2006 to point of continuing to reprise their roles: https://www.change.org/p/demand-a-sequel-to-the-beloved-movie-aquamarine-with-original-cast

At this rate it’ll take either a reboot or something set many years later, of which can confirm what the film wasn’t able to in terms of if the protagonists are still together or not.