Many pharmacologic therapies are being used or proposed for treating patients with COVID-19, but an expert panel of the Infectious Diseases Society of America (IDSA) says there's not yet sufficient evidence to recommend any of them. The IDSA issued interim guidelines on medications for patients admitted to the hospital with COVID-19, most of which recommend their use only in the context of clinical trials — or not at all. 

Remdesivir Debate 
Information on the outcomes of patients who received Gilead Sciences' experimental drug remdesivir under compassionate use protocols, published last Friday, sparked much discussion and sharply diverging viewpoints among physicians on Twitter. More than 5000 tweets by physicians have mentioned remdesivir in the past 3 days, according to data from the healthcare social media monitoring service, Symplur. 

An open-label, randomized controlled trial of remdesivir is ongoing, but Medscape contributor John M. Mandrola, MD, recommends adding clinician blinding with a placebo infusion to the standard care control arms of the trial, he writes in an open letter to Gilead. "You don't want to spend millions of dollars and end up with a biased result.

Are Coronavirus Tests Fast-Tracked by FDA Accurate?
In the current COVID-19 pandemic, the US Food and Drug Administration (FDA) has allowed diagnostic tests for SARS-CoV-2 onto the market under looser-than-normal rules that don't require manufacturers to run clinical studies to prove their tests' accuracy. While this makes more tests available more quickly, the lack of clinical data has raised concerns about the prevalence of false negative results, ProPublica reports. 

 
"In diagnostic tests in particular, it's very difficult to know if something is failing," a former director of the FDA's Office of In Vitro Diagnostics and Radiological Health said. "When are you getting more erroneous results than you should? It's not always easy to figure out."

Too many problems and no solutions. 
USA is not prepared to deal with pandemic. Please contact your government officials.