Topic

cancer

114 petitions

Update posted 1 day ago

Petition to Dianne Feinstein, Kamala D. Harris, Gavin Newsom, Boeing, Senator Henry Stern, Meredith Williams, Mohsen Nazemi, Julia Brownley, Jared Blumenfeld

No more kids with cancer: clean up the Santa Susana Field Lab

When my daughter Grace Ellen was diagnosed with a very rare form of cancer, at age four, I thought that our family had the worst, most devastating luck. But after spending months in the hospital with her, we learned that she was one of over 50 children who may have been poisoned by one of the worst nuclear meltdowns in America. Sign to demand that governor Gavin Newsom push the Department of Toxic Substances Control (DTSC) to completely clean the Santa Susana Field Lab and prevent any more children from getting cancer. Grace Ellen’s form of cancer was incredibly aggressive. At age four she was put on several clinical trials, had ten times the normal amount of chemotherapy, and spent two years fighting her cancer. A year and a half later her cancer came back and she underwent a bone marrow transplant. She was unable to walk or eat or drink, and had to fight for her life in the hospital isolation floor. Her childhood was stolen from her, and it haunts me to know her cancer might have been avoidable. She, like the other 50 children, grew up within 20 miles the Santa Susana Field Lab, land which was developed in the 1940s to conduct nuclear research. In 1959 an uncontained partial meltdown of a sodium reactor caused such a devastating radiation leak that many consider it to be the worst nuclear disaster in U.S. history – and it was completely covered up for years. Our community has up to 60% higher cancer rates, 20% higher invasive breast cancer rates, we have the reports to prove it. It is the Department of Toxic Substance Control’s job to clean up this mess. They know our children are sick and dying, but they aren’t taking any meaningful action against those who own the land – Boeing, NASA and the DOE. The Woolsey Fire, which began on Santa Susana Field Lab, may have exposed millions of people in Southern California to the chemical and radioactive waste from the site, via ash and smoke. It proved once again that we will not be safe until the site is 100% cleaned up. I will protect my children even if I have to tear down mountains with my bare hands – and I am one of many parents fighting for our kids. To win this, we need our governor to push the corrupt Department of Toxic Substances to clean up this disaster once and for all. Will you join us? 

Melissa Bumstead
616,222 supporters
Started 1 day ago

Petition to VentureWell , emily kight

Support for Affordable and Non-invasive Urine Test for Ovarian Cancer Recurrence

Problem: After treatment and surgery for ovarian cancer, there is a 70% chance of recurrence of the disease. Given the symptoms are easily missed, finding new non-invasive and affordable ways to detect early symptoms of the disease could help women stay a step ahead. Catching the disease in early stages gives better survival outcomes.  Many patients can use a blood test like CA-125 but the test misses 50% of early OC cases. Although CA125 is routinely used in clinical practice, it suffers from limited diagnostic performance due to poor sensitivity and specificity. Some OC cases only express low levels which are hard to detect. The human epididymis protein 4 (HE4) has been approved by the Food and Drug Administration for monitoring recurrence or progression of epithelial ovarian cancer in blood. Human epididymis protein 4 (HE4) is overexpressed in ovarian carcinomas and can be detected in serum with high sensitivity and specificity. However, this requires a woman to come into a doctor's office and get blood work down. It also costs $650 per test on average.  Solution: Research reported HE4 to also be a urine marker for ovarian neoplasms with improved sensitivity in early disease compared to HE4 in serum [2]. HE4 is expressed and secreted from about 90% of serous ovarian cancers, and in most endometroid and clear cell ovarian cancers.  What if there was an affordable way to test urine for He4? There is!  Using lateral flow assay technology, unique bioactive gold nanoparticles are conjugated to HE4 antibodies in a sandwich assay to detect the HE4 biomarker in urine. The difference in the amount of HE4 in the urine can indicate presence of disease via a test line. This uses the same technology as a pregnancy test but with different antibodies and a different biomarker.  After a patient gets a "No Evidence of Disease" (NED) from her doctor, the patient can take this test to establish a baseline level to compare regular testing to. The results can help a patient schedule further testing at the earliest signs of possible recurrence of the disease.  The urine test can be used as a semi-quantitative test for levels of HE4 in urine. Monitoring HE4 levels can aid in decreasing the chance of reoccurrence of the disease into a later stage. Urine offers a convenient and less harmful sampling procedure for the patient, especially for repeated testing over an extended time period. This repeated testing can aid in the earlier detection of cancer development, as well as monitoring early therapy responses.  A patient can test their own urine in their own home. While ovarian cancer is not as common as other cancers, it is the fifth leading cause of cancer deaths due to delay in diagnosis, that is, 60–70% of cases are typically diagnosed at the later stages with a 5-year survival rate < 40% [3]. About Me: I am a bioengineering senior at Temple University in Philadelphia. I have built the proof of principle to demonstrate the test could work in but we are in need of more funding to validate this test using more urine samples from OC patients. I was only able to afford buying a few OC urine samples with the initial testing (each urine sample costs $200).  How to Help:  I have applied to VentureWell program to get $20K for the project to continue. They requested I get more evidence this type of test would be wanted by the demographic (patients, patient families, & their doctors). So with your signature I can show the committee that this type of test is worth working on to help women globally stay one step ahead!      References 1.      Jemal A, et al. CA Cancer J Clin 2011;61:69-90 2. 2.      Hellström I, et al. Cancer lett 2010;296:43-48 3. 3.      Moore RG, et al. Gynecol Oncol 2009; 112:40-46  

Emily Kight
241 supporters
Update posted 2 days ago

Petition to Scott Gottlieb MD, Jeff Shuren, Sybill Storz, Managing Director, Hal Lawrence, William Maisel MD

Health Alert: Many Women Have Died Unnecessarily Because Dangerous Cancers of the Uterus and Ovaries Are Being Spread using MORCELLATORS. Stop MORCELLATION in Minimally Invasive Gynecological Surgery.

Friends of the Public, Many women have been harmed and have died prematurely or unnecessarily because of a routine but avoidable gynecological practice known as MORCELLATION. This world-wide practice has devastated many families for well over two decades now. More than 600,000 hysterectomies are done in the US every year. By the age of 70, one out of every three American women will have had a hysterectomy. About 90% of these surgeries are done for what is presumed to be a benign condition called fibroids. More and more of these surgeries are done with minimally invasive techniques.  Usually, to get the uterus out of the body using the "minimally invasive" technique, it is cut into small pieces with a machine called a morcellator.  However, a devastating problem happens if in fact the woman did NOT have fibroids – but if she actually had cancer.  Unfortunately, the tests that are done before a hysterectomy do not identify these cancers well.  Many gynecologists don't even bother getting any tests. In fact, morcellating cancer spreads the cancer inside the woman’s body.   This is called ‘up staging’ the cancer.  It is important to understand: 1) The average life span following accidental morcellation of sarcoma is only 24-36 months. 2) Only 15% of woman who have leiomyosarcoma (LMS) that has spread (stage 4) will be alive after 5 years. 3) Women with sarcoma who are morcellated are about 4 times more likely to die from sarcoma than if they had not been morcellated.  This is an avoidable disaster. This problem has been recognized for more than two decades.  A review of the literature, by the Food and Drug Administration, revealed that 1 in 350 women who go for fibroid surgery actually have sarcoma.  This means that everyday 2-5 women in the US – and more around the world are susceptible to having a deadly cancer spread because of morcellation. This catastrophic problem has happened in my family and we are fighting to stop this dangerous activity called morcellation.  A chance of 1 in 350 for such a devastating outcome is much too high to accept.  Women should be told the truth and the practice should stop. Please help us bring an end to spreading cancer with morcellation.  This is a totally AVOIDABLE practice.  People need to understand their options, which include hysterectomy through a mini-lapartomy incision or trans-vaginally – but – up until recently, most women never heard anything about morcellation or about the possibility of cancer upstaging. And, if they do, this risk is down-played by most minimally invasive gynecologists. We can tell you based on our experience, when cancers are spread by morcellation, the outcomes can be devastating - because the cancer is upstaged. We need your help. Please sign our petition so we can get the word out.  We want the American College of Obstetricians and Gynecologists and the American Board of Obstetrics and Gynecology to change this "standard of care" by ending the needless waste of life caused by spreading cancer with morcellation. For more information and original references see: http://journals.lww.com/oncology-times/blog/onlinefirst/pages/post.aspx?PostID=188 ) (also see:http://www.ncbi.nlm.nih.gov/pubmed/23189178) (also see:http://www.ncbi.nlm.nih.gov/pubmed/21565389). The attached video below shows an example of morcellation https://www.youtube.com/watch?v=nPkKw0j-aXE The following companies manufacture and distribute uterine morcellator devices: 1) ETHICON: Gynecare morcellator 2) Storz: Rotocut Morcellator 3) Richard Wolf Medical Instrumentation Company 4) LiNA: LiNA Xcise Cordless Laparoscopic Morcellator 5) Blue Endo MOREsolution Tissue Morcellator 6) Pneumoliner Power Morcellation System by Olympus Corporation. Intuitive Surgical's Da Vinci Robot deserves special mention, as the frequency of robotic hysterectomies performed by minimally invasive gynecologists is currently on the rise across the United States. Note that Intuitive Surgical builds and markets the DaVinci robot, which is not itself a "morcellator". However, use of the DaVinci robot almost invariably appears to require that the uterus be minced up, or morcellated, into smaller pieces inside the woman's belly cavity in order to extract from the abdomen. A clear example is shown in the following YouTube video of DaVinci being used to perform a robotic hysterectomy and manually morcellating the uterus using the endo-wrist component of the robot (morcellation is being performed at minute 5:30 of the video).  https://www.youtube.com/watch?v=f6luiX6UQmg  Without morcellation using equipment manufactured by Intuitive Surgical, robotic hysterectomies would, likely, not be possible using the DaVinci Robot. It is noteworthy that the DaVinci robot does not appear to have a readily available warning label advising against its use to morcellate tumors with malignant potential inside the body. The company's Chief Medical Advisor, Dr. Myriam Curet, a surgeon herself, has been informed and advised of this severe hazard in the use of DaVinci for robotic hysterectomy and the absence of a readily available warning label.

Hooman Noorchashm
95,701 supporters
Update posted 4 days ago

Petition to Dr.H.Bliss Murphy Cancer Clinic, The Government of Newfoundland and Labrador

Designate parking spaces close to the hospital for cancer patients receiving treatment.

There is no parking made available for cancer patients at the Dr.H.Bliss Murphy cancer clinic. What can the Cancer clinic do? • Provide a designated parking area for cancer patientswith enough spaces( we are looking for 25 spots). Use a boomgate and/or apermit system to make sure only eligible patients canpark there, and enforce it. Cars can be towed and tickets issued just like the blue zones. • Use a permit system such as windscreen stickers,swipe cards or dashboard passes, with expiry datesor color coding to show patients with currentappointments. Having a designated parking area close to the hospital for cancer patients who are receiving treatment is vital.We are fighting the biggest battle of our lives and having the stress of parking should not be one of them.  I was late for an appointment at the cancer clinic because it took me 45 minutes to find a place to park.The long walk to the entrance of the hospital was exhausting.I see a lot of people who are receiving treatment at the Dr.H.Bliss Murphy cancer clinic and many are seniors.This parking problem has to be addressed because it has been a problem for these patients for years.Designated parking is needed for cancer patients and those spots need to be close to the entrance of the cancer clinic. I started this petition because many cancer patients talked about the problem with the parking and how frustrating it is to find a place to park going to the Dr.H.Bliss Murphy cancer clinic. I hope the hospital can designate an area for cancer patients close to the clinic.It would make this journey more easier on the patients.   Another part of this advocacy we have voiced our concern is Smoking.It should be prohibited from the cancer clinic and the HSC.People are smoking in the entrances and then throwing cigarette butts to the ground.Take a walk in front of the cancer clinic one day and you will see just that...A beautiful garden there but sadly many butts on the ground. Even though there is an announcement stating smoking is not permitted on the grounds people still are doing just that. Hospitals and clinics should be Smoke free zones.      

Susan Glynn
25,147 supporters