Raise more awareness about Sickle Cell Disease, Sickle Cell Trait and Thalassemia.

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Hello, my name is Sam and I have been an advocate, friend and representative for the Sickle Cell Disease, Sickle Cell Trait and Thalassemia Community since 2014. A lot of people have died from Sickle Cell Disease recently because of neglect, mistreatment by doctors and nurses and lack of awareness and it needs to stop. Awareness of Sickle Cell Disease, Sickle Cell Trait and Thalassemia are often overlooked and don't receive the awareness and recognition that they desperately  need.  Sickle Cell Disease affects millions of people worldwide. It is most common among people whose ancestors come from Africa; Mediterranean countries such as Greece, Turkey, and Italy; the Arabian Peninsula; India; and Spanish-speaking regions in South America, Central America, and parts of the Caribbean. It's most common in America, Africa, the Caribbean, Mediterranean and India It is a blood disorder. It affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disorder have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape. Signs and symptoms of sickle cell disease usually begin in early childhood. Characteristic features of this disorder include a low number of red blood cells (anemia), repeated infections, and periodic episodes of pain. A pain crisis can last anywhere from a few minutes to a few hours to a few months.Hand-Foot Syndrome occurs when sickle-shaped RBCs block blood vessels in the hands or feet. This causes the hands and feet to swell. It can also cause leg ulcers. Swollen hands and feet are often the first sign of sickle cell anemia in babies.

Hemoglobin SS disease is the most common type of sickle cell disease. It occurs when you inherit copies of the hemoglobin S gene from both parents. This forms hemoglobin known as Hb SS. Hemoglobin SC Disease

Hemoglobin SC disease is the second most common type of sickle cell disease. It occurs when you inherit the Hb C gene from one parent and the Hb S gene from the other. Individuals with Hb SC have similar symptoms to individuals with Hb SS. However, the anemia is less severe. Hemoglobin SB+ (Beta) Thalassemia

Hemoglobin SB+ (Beta) thalassemia affects beta globin gene production. The size of the red blood cell is reduced because less beta protein is made. If inherited with the Hb S gene, you will have Hemoglobin S Beta thalassemia. Beta-Zero Thalassemia

Beta-Zero thalassemia is the second type of beta thalassemia. It has similar symptoms to Hb SS anemia. However, sometimes the symptoms of beta-zero thalassemia are more severe. It is associated with a poorer prognosis.

People who only inherit a mutated gene from only one parent are said to have sickle cell trait. They may have no symptoms or reduced symptoms. They can have symptoms if overexertion or if they get dehydrated. Altitude changes( high altitudes) can also cause them to have symptoms because the percentage oxygen saturation of hemoglobin determines the content of oxygen in blood. After the human body reaches around 2,100 m (7,000 feet) above sea level, the saturation of oxyhemoglobin begins to plummet.

The Spleen and the bladder are the organs that are usually removed before adulthood.

The leading cause of death for people who have Sickle Cell Disease is Acute Chest Syndrome.

People should support it so we can help get more research and save lives. We need a cure. If people signed this, it would make a difference because there would be better research and lives would be saved.

 

https://www.facebook.com/sam.blase.7/videos/vb.100000079162553/881631041849526/?type=3&theater This is my awareness slideshow that I made back in 2014.



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