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Susan M. Collins

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Petitioning Bernie Sanders

FDA Accelerated Approval of Genervon's GM604 for Use In ALS

My name is Nick and I am 54-years old. In October 2011, I was diagnosed with ALS. Today, I am in a wheelchair and cannot walk or stand. My arms grow weaker almost every day and my breathing is starting to be affected. I used to be very active but now I can only leave my home when I have someone with me who's strong enough to lift me into my wheelchair once I'm done scooting down to the bottom of the stairs on my butt. It can feel like I'm a 100-year old man who can't do things for himself anymore. At 54, I should still be a vibrant part of my community, but this disease is kicking me where it hurts. Through the enthusiasm generated by the Ice Bucket Challenge, many people now know that ALS is a degenerative neurological disease that currently affects over 30,000 Americans, and as it stands the disease is always fatal. Most people with ALS are given only 2-5 years to live. When I was diagnosed, I was devastated - it took me months to accept it. Although I am now resolved, I have not lost hope. Currently, there is only one drug available to treat ALS (Riluzole) and it is only able to extend life expectancy by a couple months. That's why the recent news about a small company named Genervon Biopharmaceuticals and their trial drug "GM604" has been so exciting for the Global ALS Community. While most trials have a hard time even finding a positive trend, the GM604 trial data supports the view that this drug could very well be is a game changer in the battle against ALS. There are multiple, statistically significant data. Not only in clinical data and results alone, but also correlated biomarkers data and results as well. (Please see "Files" section on the campaign website: https://sites.google.com/site/aap4gm6/) Genervon met with the FDA in February 2015 and made a potentially life-changing request on behalf of the ALS community; they asked the FDA to promote GM604 to the Accelerated Approval Program with Post-Marketing Phase 4 Requirements, so all ALS patients can have legal access to GM604 now. Under the FDA's Accelerated Approval Program, the treatments would be covered by health insurance. Although Genervon knows that this request might complicate their relationship with the FDA, they were willing to take a stand and do everything they can to help the ALS community because it is the right thing to do. If the FDA does not grant Accelerated Approval, it will likely be 3 more years before patients are able to access this drug -- meaning that most people currently living with ALS will not live to see it reach market. While acknowledging the paramount importance of public safety in the FDA’s drug approval process, I believe that ALS presents a compelling case for an exception to the usual process. I am asking you to help me appeal to the FDA through their sense of compassion for those of us with this dreadful illness. People with ALS don't have time to wait for another clinical trial to be completed.  By signing this petition, you'll be helping patients like me request that the FDA expidite the way potentially life-saving treatments are made accessible to people with ALS -- starting right now with GM604. Doing so could very likely mean a change in the course of ALS progression not only for myself, but hundreds of thousands of other patients worldwide. After you sign, please follow this link to tweet and/or email the FDA: https://www.change.org/p/lisa-murkowski-fda-accelerated-approval-of-genervon-s-gm604-for-use-in-als/u/9475826 Thank you, Nick Like us on Facebook: https://www.facebook.com/gm604forals Please go to the Genervon website for a true understanding of the facts and the science behind GM604: http://www.genervon.com/genervon/about_pressreleases.php  

Nicholas Grillo
801,493 supporters
Closed
Petitioning Wells Fargo, Tim Sloan, Carrie. L. Tolstedt, Wells Fargo Board of Directors, Lee Zeldin, Kenneth LaValle, Avid Modjtabai, Franklin Codel, Andrew Cecere, Richard Davis, New York Governor, New York S...

Help save mom's home!

Three generations of our family have lived in our mother’s home. She has been living there for over 50 years and her favorite part is her yard, which she has lovingly tended to ever since we can remember.  Mom is an 85-year-old, a breast cancer survivor, with Alzheimer's Disease. Her home has always been one of the most meaningful parts of her life. It is all about to be taken away. Our mother is one of many Wells Fargo predatory lending victims. Mom was living alone when Wells Fargo approached her and interviewed her for a number of loan applications. Despite being elderly and living on a fixed Social Security income, they gave her two mortgage loans. When she was about to default on one, they issued a third. How could Wells Fargo give her loans that they knew she couldn’t possibly afford? Our mother had no idea she was trapped in a predatory lending scheme, the type that Wells Fargo has been found guilty of doing time and time again. By the time we realized how much trouble mom was in, it was too late to intervene. The statute of limitations for predatory lending had run out and Wells Fargo was on her doorstep coming to collect the house. An attorney for Wells Fargo recently told our family that they, “are not in the business of running a nursing home.”  We have little time to prevent this foreclosure sale from occurring or she will be torn away from her home. This will surely leave her devastated and confused -- a fate she does not deserve. Please sign our petition and tell Wells Fargo to let our mom stay in her beloved home where she belongs.  Thank you!

Save Mom's Home
138,298 supporters
Petitioning Susan M. Collins

Tell Susan Collins to Save Reproductive Rights

We are facing the most serious threat to abortion rights in 45 years. With the retirement of Supreme Court Justice Anthony Kennedy, President Trump has fulfilled his campaign promise to nominate a highly conservative judge who could overturn Roe v. Wade by nominating Judge Brett Kavanaugh. His nomination could give states the right to outlaw abortion -- ending the right to safe and legal abortion for women across the country. As a mother of two, I had the right and privilege to choose the size and timing of my family; it terrifies me that my sons, nieces, and nephews may not have the same.  But there's still a chance to protect reproductive rights. My senator, Republican Senator Susan Collins, could have the deciding vote on Judge Kavanaugh’s nomination for the court – will you join me in asking her to reject his nomination? If Sen. Collins doesn't block Judge Kavanaugh, it’s likely that over 20 states could quickly enact severe restrictions or complete bans on abortion. This means women who can afford it will have to travel out of state to get the care they need. But many won't be able to afford it – which could lead to significant increases in injury and death due to people attempting to terminate their own pregnancies. As the rest of the world progresses forward, we can not stand for the United States to go back. If all 49 Democratic senators vote against Judge Kavanaugh, just one more vote could block their nomination and save access to legal abortion. Sen. Collins is just the person to cast that critical vote. Our reproductive rights have never been in more danger than they are right now. Sign now to tell Senator Collins she must reject Judge Kavanaugh and preserve the right for millions of women to obtain safe and legal access to reproductive care. Remind Collins that however she votes, this will be her LASTING legacy to her country.

Abby King
130,642 supporters