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Susan Collins

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Petitioning Bernie Sanders

FDA Accelerated Approval of Genervon's GM604 for Use In ALS

My name is Nick and I am 54-years old. In October 2011, I was diagnosed with ALS. Today, I am in a wheelchair and cannot walk or stand. My arms grow weaker almost every day and my breathing is starting to be affected. I used to be very active but now I can only leave my home when I have someone with me who's strong enough to lift me into my wheelchair once I'm done scooting down to the bottom of the stairs on my butt. It can feel like I'm a 100-year old man who can't do things for himself anymore. At 54, I should still be a vibrant part of my community, but this disease is kicking me where it hurts. Through the enthusiasm generated by the Ice Bucket Challenge, many people now know that ALS is a degenerative neurological disease that currently affects over 30,000 Americans, and as it stands the disease is always fatal. Most people with ALS are given only 2-5 years to live. When I was diagnosed, I was devastated - it took me months to accept it. Although I am now resolved, I have not lost hope. Currently, there is only one drug available to treat ALS (Riluzole) and it is only able to extend life expectancy by a couple months. That's why the recent news about a small company named Genervon Biopharmaceuticals and their trial drug "GM604" has been so exciting for the Global ALS Community. While most trials have a hard time even finding a positive trend, the GM604 trial data supports the view that this drug could very well be is a game changer in the battle against ALS. There are multiple, statistically significant data. Not only in clinical data and results alone, but also correlated biomarkers data and results as well. (Please see "Files" section on the campaign website: https://sites.google.com/site/aap4gm6/) Genervon met with the FDA in February 2015 and made a potentially life-changing request on behalf of the ALS community; they asked the FDA to promote GM604 to the Accelerated Approval Program with Post-Marketing Phase 4 Requirements, so all ALS patients can have legal access to GM604 now. Under the FDA's Accelerated Approval Program, the treatments would be covered by health insurance. Although Genervon knows that this request might complicate their relationship with the FDA, they were willing to take a stand and do everything they can to help the ALS community because it is the right thing to do. If the FDA does not grant Accelerated Approval, it will likely be 3 more years before patients are able to access this drug -- meaning that most people currently living with ALS will not live to see it reach market. While acknowledging the paramount importance of public safety in the FDA’s drug approval process, I believe that ALS presents a compelling case for an exception to the usual process. I am asking you to help me appeal to the FDA through their sense of compassion for those of us with this dreadful illness. People with ALS don't have time to wait for another clinical trial to be completed.  By signing this petition, you'll be helping patients like me request that the FDA expidite the way potentially life-saving treatments are made accessible to people with ALS -- starting right now with GM604. Doing so could very likely mean a change in the course of ALS progression not only for myself, but hundreds of thousands of other patients worldwide. After you sign, please follow this link to tweet and/or email the FDA: https://www.change.org/p/lisa-murkowski-fda-accelerated-approval-of-genervon-s-gm604-for-use-in-als/u/9475826 Thank you, Nick Like us on Facebook: https://www.facebook.com/gm604forals Please go to the Genervon website for a true understanding of the facts and the science behind GM604: http://www.genervon.com/genervon/about_pressreleases.php  

Nicholas Grillo
800,867 supporters
Petitioning Food and Drug Administration

Tell the FDA to stop denying ALS patients treatment options

When I became a parent, I knew immediately that I would do anything to protect my daughters from the hardest parts of life. My mission would be to give them as much love and comfort as I possibly could. But now instead of me taking care of them, my daughters are often responsible for taking care of me, because in May of 2014 I was diagnosed with ALS. Now, instead of protecting them, my daughters are forced to watch as my body dies one muscle at a time. ALS is a devastating disease, that currently has no effective FDA approved treatments. However, there are promising therapies in the FDA approval pipeline that might improve my chances and quality of life, but the FDA isn’t willing to expedite the approval of these drugs, even though the average life expectancy of an ALS patient is 3-5 years and the average time it takes for a drug to become FDA approved is over a decade.   Please join me and Hope NOW for ALS in petitioning Congress and the FDA to apply Accelerated Approvals (AAP) to promising treatments targeting terminal diseases, and implement faster, smarter, and more humane clinical trials using today’s science. This is not a radical or new idea. In 1992, in response to the HIV/AIDS epidemic, the FDA adopted the Accelerated Approval Program (AAP) – an expedited approval process to treat fatal diseases. This was a process to allow patients fast access to potentially life saving drugs, and has since been used for cancer and heart failure treatments. But the FDA refuses to apply it to ALS and other rapidly fatal diseases. How can it possibly be fair to exclude the most vulnerable and at risk people -- those with fast acting terminal diseases -- from this program? ALS is always fatal, and there are currently over 30,000 patients in the US with no options. We need help. We need options. My diagnosis is the greatest challenge my family has ever faced, and my daughters have amazed me with their grace and strength in taking on this battle with me. I know that even though my life has not turned out like I imagined it, I can still be the dad I always wanted to be, and I can still show my daughters what it means to take a stand for what counts. Please join me and Hope NOW for ALS to help save my life, and the lives of so many others around the country.

Jay Smith with Hope Now for ALS
188,798 supporters
Closed
Petitioning Wells Fargo, Tim Sloan, Carrie. L. Tolstedt, Wells Fargo Board of Directors, Lee Zeldin, Kenneth LaValle, Avid Modjtabai, Franklin Codel, Andrew Cecere, Richard Davis, New York Governor, New York S...

Help save mom's home!

Three generations of our family have lived in our mother’s home. She has been living there for over 50 years and her favorite part is her yard, which she has lovingly tended to ever since we can remember.  Mom is an 85-year-old, a breast cancer survivor, with Alzheimer's Disease. Her home has always been one of the most meaningful parts of her life. It is all about to be taken away. Our mother is one of many Wells Fargo predatory lending victims. Mom was living alone when Wells Fargo approached her and interviewed her for a number of loan applications. Despite being elderly and living on a fixed Social Security income, they gave her two mortgage loans. When she was about to default on one, they issued a third. How could Wells Fargo give her loans that they knew she couldn’t possibly afford? Our mother had no idea she was trapped in a predatory lending scheme, the type that Wells Fargo has been found guilty of doing time and time again. By the time we realized how much trouble mom was in, it was too late to intervene. The statute of limitations for predatory lending had run out and Wells Fargo was on her doorstep coming to collect the house. An attorney for Wells Fargo recently told our family that they, “are not in the business of running a nursing home.”  We have little time to prevent this foreclosure sale from occurring or she will be torn away from her home. This will surely leave her devastated and confused -- a fate she does not deserve. Please sign our petition and tell Wells Fargo to let our mom stay in her beloved home where she belongs.  Thank you!

Save Mom's Home
138,405 supporters
Petitioning Susan Collins

Tell Susan Collins to Save Reproductive Rights

We are facing the most serious threat to abortion rights in 45 years. With the retirement of Supreme Court Justice Anthony Kennedy, President Trump has fulfilled his campaign promise to nominate a highly conservative judge who could overturn Roe v. Wade by nominating Judge Brett Kavanaugh. His nomination could give states the right to outlaw abortion -- ending the right to safe and legal abortion for women across the country. As a mother of two, I had the right and privilege to choose the size and timing of my family; it terrifies me that my sons, nieces, and nephews may not have the same.  But there's still a chance to protect reproductive rights. My senator, Republican Senator Susan Collins, could have the deciding vote on Judge Kavanaugh’s nomination for the court – will you join me in asking her to reject his nomination? If Sen. Collins doesn't block Judge Kavanaugh, it’s likely that over 20 states could quickly enact severe restrictions or complete bans on abortion. This means women who can afford it will have to travel out of state to get the care they need. But many won't be able to afford it – which could lead to significant increases in injury and death due to people attempting to terminate their own pregnancies. As the rest of the world progresses forward, we can not stand for the United States to go back. If all 49 Democratic senators vote against Judge Kavanaugh, just one more vote could block their nomination and save access to legal abortion. Sen. Collins is just the person to cast that critical vote. Our reproductive rights have never been in more danger than they are right now. Sign now to tell Senator Collins she must reject Judge Kavanaugh and preserve the right for millions of women to obtain safe and legal access to reproductive care. Remind Collins that however she votes, this will be her LASTING legacy to her country.

Abby King
74,134 supporters
Victory
Petitioning U.S. Senate, Kamala Harris, John McCain, Dean Heller, Susan Collins, Joni Ernst, Shelley Capito, Rand Paul, Lisa Murkowski

Tell the Senate to vote NO on Graham-Cassidy Healthcare Bill

We call on Senate to vote no on the Graham-Cassidy bill. Passage of this bill would result in millions of Americans across the country losing healthcare coverage. Approval of this bill would also result in massive cuts to the Medicaid program, sharply reducing or eliminating coverage for people who have disabilities, individuals living in poverty, and other vulnerable persons. We call upon Congress to work in an orderly, non-partisan, and meaningful way to find solutions that address problems with the Affordable Care Act that result in improved healthcare for all Americans.

Ceren Guven
42,664 supporters
Petitioning Charles Schumer, Tammy Baldwin, Michael Bennet, Richard Blumenthal, Sherrod Brown, Maria Cantwell, Ben Cardin, Tom Carper, Catherine Cortez Masto, Joe Donnelly, Tammy Duckworth, Dick Durbin, DIane ...

Congress: Censure President Trump For His Heinous Remarks About "Shithole" Countries

Please also sign and share our net neutrality petition: https://www.change.org/p/jeff-flake-we-need-one-more-republican-vote-in-the-senate-to-save-net-neutrality And join our group here: https://www.facebook.com/groups/1721640631484675/     ----------- This petition began in a private, politically active facebook group of 6300 people consisting of Democrats, Independents, Socialists, Libertarians, and concerned Republicans.  On Thursday, Jan 11, the Washington Post reported that President Donald Trump attacked potential immigrants from Haiti, El Salvador and African countries as part of a bipartisan immigration deal. The White House did not deny these allegations. This, a day before the 8th anniversary of the earthquake in Haiti that killed over 100,000 people.  This is a step too far. If this were any other president, a censure would be an expected course of action. We realize that many in congress have become numb to Mr. Trump's rhetoric, but American voters have not. This is the language of fringe talk radio, not the President of the United States. He dishonors the office with these words. He is our chief diplomat around the world, and he represents millions of Americans who emigrated from these nations. He should act like it. It is time for congress to stand up and censure this president for his dishonorable remarks about our friends in Haiti, El Salvador and Africa, who rightfully look to the United States as a beacon of freedom and opportunity.  

Countdown To Beat Trump (https://www.facebook.com/groups/1721640631484675/)
37,738 supporters
Victory
Petitioning Barbara Mikulski

We Demand that the U. S. Senate not confirm Andrew Puzder as Secretary of Labor

Andrew Puzder is among Trump's more controversial Cabinet picks because he has publicly opposed the overtime rule and various other Department of Labor regulations, and because the fast-food industry, from which Puzder hails, is a top wage-theft enforcement target at the department. Puzder is CEO of CKE Restaurants, which includes Carl’s Jr. and Hardee's. It’s actually very hard to imagine a worse choice for Labor Secretary than Andy Puzder. The Labor Secretary’s job is to look out for American workers. Trump's Labor nominee has opposed increasing the federal minimum wage from $7.25 an hour to $10.10 an hour and efforts to expand eligibility for overtime pay.   It would be kind of funny if it wasn’t so serious. During the election, Trump made a lot of promises to create good jobs. But he’s filling his cabinet with CEOs and right-wing billionaires who have spent their lives undermining working people’s rights to come together in unions, while fighting minimum wage increases, paid sick leave and family leave policies. The evidence clearly demonstrates that protecting the rights of the people who work at Puzder’s company or its franchisees doesn't seem to be his priority. Puzder has run a business model that has produced widespread labor abuses at the companies. According to data compiled by Bloomberg BNA, over the previous seven years, about 60 percent of all Labor Department investigations of Carl's Jr. Restaurants found violations of the Fair Labor Standards Act. While working people at his fast food chains sometimes were making below minimum wage, Puzder was taking big compensation packages. In 2012, he made 291 times as much as workers at his restaurants. Now, he could be in charge of enforcing our nation’s labor laws—from ensuring workplace safety to investigating wage theft.  His companies had the fourth highest incidents of wage theft reported to the government.  ‘Wage theft is a rampant, everyday problem in the fast-food industry: Nearly nine out of 10 fast-food workers across the country report having money stolen from their paychecks by their boss,’ Kendall Fells, the Fight for $15 national organizing director, told Bloomberg BNA via e-mail. Bloomberg reported. “Fells referred to a 2014 poll commissioned by the campaign of more than 1,000 fast-food workers nationwide. The survey documented such common worker complaints as being forced to perform tasks before clocking in or after clocking out, having the cost of uniforms deducted from their paychecks, and not receiving breaks during long shifts.”  Puzder’s Carl’s Jr. restaurant chain also has a history of sexist television. He thinks it’s appropriate to peddle sex to kids if it sells the product. “We believe in putting hot models in our commercials, because ugly ones don’t sell burgers,” said the CEO in a 2011 press release, according to Fortune. “We target hungry guys, and we get young kids that want to be young hungry guys.” Let’s target Puzder’s nomination instead. Just Say No Puzder at Labor. This petition will be delivered to the full Senate and to the Health, Education, Labor, and Pensions Committee of the U.S. Senate

TRO Political Action Network Truth. Resistance. Opposition.
37,591 supporters
Petitioning President of the United States, US department of commerce, Census Bureau, U.S. House of Representatives, U.S. Senate, Donald Trump, Paul Ryan, Dana Rohrabacher, Seth Moulton, Jim McGovern, Jim Cost...

Remove sub-Asian boxes on Census Form 2020! Stop racist anti-Asian anti-immigrant legacy!

Dear fellow Americans for justice, brothers and sisters against racism, The glaringly racist legacy of sub-Asian boxes on the Census form was started in 1870, after the Burlingame Treaty of 1868, which eventually led to the infamous, racist, and inhumane Chinese Exclusion Act spanning from 1882 to 1943, which among other terrible abominations, banned U.S. residents of Chinese descent from having children or getting married; their family members in Asia were forbidden from entry to U.S. and reuniting as families. The Census form has no "Asian/Asian American" category. In its place are a group of boxes signifying foreign nationalities in Asia as if Asian Americans were all “perpetual foreigners.” It intrusively identified and collected data on which U.S. residents were of Chinese, Filipino, Indian, Vietnamese, Korean, Japanese...descent. While the Chinese Exclusion Act ended in 1943, did these racist, humiliating, dehumanizing sub-Asian boxes get removed from the Census form? No, they were kept on the Census form by the U.S. government even until today, and if we don't fight back and boycott the Census form with sub-Asian boxes, it will stay on the 2020 Census form and beyond, prolonging a racist American legacy, a shame to all Americans. This legacy treats Americans of Asian descent as perpetual foreigners, and collects intrusive personal ancestral origin data used in many kinds of racial discrimination and persecution. In one example, the U.S. government used information from the Census Bureau to identify native born Americans of Japanese descent and sent them to Internment Camps during the World War II. There were also discriminatory laws against Americans of various Asian descent, such as Filipino. Such horrendous trampling of humanity will happen again unless you and I act now to boycott a 2020 Census form with sub-Asian boxes. We demand these sub-Asian boxes be removed and replaced with one description--"Asian/Asian American." Injustice to one human being is injustice to all human kind. If we don't stop this racist and anti-immigrant legacy, its “logic” and mentality will be repeated in current and future policy-making. Let's keep fighting against racism and improve the human condition step by step. Please join the good fight to make this historically significant change happen for now and forever, by signing this petition and sharing it on social media and by email, word of mouth. Power to the people! Fighting on, Americans against racism and anti-Asian anti-immigrant legacy

Swan Lee
23,721 supporters
Petitioning Angus King, Susan Collins, Chellie Pingree, Paul LePage, Janet T. Mills, Sen. Scott Cyrway, Sen. Mark Dion

Attorney General Janet T. Mills: Prosecute Justin DiPietro, Courtney Roberts, and Elisha DiPietro in Connection with the Death of Ayla Reynolds.

Background On the morning of December 17, 2011, Justin DiPietro reported his 20-month old daughter Ayla Reynolds missing. After spending the day with Ayla December 16, Justin claimed he put her to bed at 8 p.m., and she was gone when he woke up in the morning. Ayla had lived in Justin’s home just 59 days. Ayla Reynolds photos linkAyla Reynolds news archives Two other adults, his sister Elisha DiPietro and his girlfriend Courtney Roberts, were in the house that night.  Justin and Courtney claimed to have slept in his basement bedroom, while Elisha claimed to have slept in her own bedroom, with her own daughter, across the hall from the bedroom Ayla normally shared with Elisha’s daughter. They insisted it was a normal night, and none of them saw or heard anything. The Investigation Investigators concluded Ayla was not kidnapped and she did not leave the house on her own accord.  They determined that foul play befell her in the house. They announced they did not expect to find Ayla alive. Some of the critical evidence included Ayla’s blood in various rooms in the house both upstairs and downstairs.  Unofficial crime scene linkThe case for Ayla blood evidence link That blood was found in baby Ayla’s bedroom on a doll; it was found in the family living room on the sofa; downstairs, where Justin and Courtney alleged to have slept unaware there was a fist-size stain of Ayla’s blood on the sheets and mattress, her blood was splattered on the wall next to the bed and on the floor. There was also blood in a pair of Justin’s shoes near the bed.  A blue plastic tote contained a sheet investigators said was used to clean up some of Ayla’s blood. Some of the blood found in the house contained saliva, indicating projectile vomiting and/or blunt force trauma. Two vehicles were parked in the DiPietro driveway. The closest to the road belonged to Courtney. The other vehicle belonged to Justin. Inside Justin’s vehicle, police found Ayla’s car seat stained with her blood. Ayla’s vomit was also present in Justin’s car. Police have searched for Ayla’s body but have yet to locate it. Justin, Courtney, and Elisha all deny knowledge of Ayla’s whereabouts. The Search for Ayla Justin DiPietro’s false report of a missing baby set off the most extensive and expensive missing child investigation in Maine’s history, costing the citizens more than $500,000.  Justice delayed is justice denied - William E. Gladstone Despite the passage of six years, there have been no arrests in the death of Ayla Reynolds or its cover-up. Trista Reynolds, Ayla’s mother, and her family, suffer with each day that passes and justice for Ayla is not forthcoming.  Please sign and share our petition seeking justice for Ayla now.

Answers for Ayla
8,840 supporters
Petitioning U.S. Senate, Richard Shelby, Dan Sullivan, Lisa Murkowski, John McCain, Jeff Flake, Tom Cotton, John Boozman, Dianne Feinstein, Cory Gardner, Michael Bennet, Chris Murphy, Richard Blumenthal, Tom C...

Say Yes To Disability Rights

On February 15th, the House of Representatives passed HR620, the so-called Americans with Disabilities Education and Reform Act. Instead of stopping the few frivolous lawsuits that occur, the bill will  roll back nearly thirty years of civil rights legislation for people with disabilities in the United States. By passing this bill, You will undo the foundation of the Americans with Disabilities Act, a piece of landmark legislation passed in 1990 that gives disabled people a chance at equal access to employment, education, and society in general. By voting yes, you will Force disabled people to endure a lengthy process that involves filing complaints with businesses when they face accessibility barriers. These businesses, some of which have violated the law for almost 30 years, will have up to six months to resolve accessibility issues, and even longer, if the businesses can demonstrate “substantial progress” toward resolution.No other civil rights law has ever put the burden on those it protects to start and maintain the enforcement process. HR620 places cost-cutting for business owners ahead of the human rights of people with disabilities. Imagine having to wait over six months to use the restroom, locate merchandise, or check out confidentially and independently when building codes and other provisions for your civil rights have existed for almost 3 decades. Republican Senator Jeff Flake of Arizona will soon introduce the bill to the rest of you in the United States Senate.Please, Senators, we urge you to vote against this unacceptable and unfair legislation. Do not weaken the Americans with Disabilities Act. Do not weaken current and future civil rights legislation for everyone by placing the responsibility for enforcement on those who need protection.Thank you for your attention.

Sabra Ewing
7,841 supporters