Giving should come naturally. I don't think we need to stress over the absolute best possible place. There are so many nonprofits doing great work that it would be hard to go wrong. If someone is already an "involved giver," it shouldn't be difficult to decide if a charity is using its resources wisely and achieving a worthwhile mission. Other than that, I plan to look within to decide what most matches my values and how I see the world. I'd rather spend time and energy doing that than scouring a 990 form.